PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collections
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Browsing PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collections by Department "KTÜN"
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Article Adaptation and Validation of the Post-Pandemic Health Promotion Behavior of Young Adults in the Digital Age (ps-Sgd) Scale in the Turkish Population(MDPI, 2024) Koç, Mustafa Can; Yıldırım, Elif; Özdurak Singin, Rabia Hürrem; Talaghir, Laurentiu-Gabriel; Iconomescu, Teodora Mihaela; Karakaş, NeşeBackground: Young adulthood is a critical developmental period in which individuals establish life-long health behaviors and take responsibility for their own health care. Health promotion strategies tailored to young adults, leveraging digital tools, and addressing challenges exacerbated by events like the COVID-19 pandemic are needed. The aim of this study was to adapt the post-pandemic health promotion behavior of young adults in the digital age (PS-SGD) scale to the Turkish population in order to assess and compare the health behavior of young adults after the pandemic. Methods: A total of 312 participants, aged between 19 and 29 years, were included in the study via non-probabilistic criterion sampling, while the Turkish adaptation process started with translation and back translation methods performed with three language and two health science experts. For statistical analysis, EFA and CFA were conducted to evaluate internal consistency and structural validity. Confirmatory factor analysis was utilized to confirm the structure of the six sub-dimensions. Additionally, measurement invariance was examined regarding participants' gender to determine if the scale accurately captured similar traits across diverse groups. The relationship between the test-retest data was tested by Pearson correlation to measure consistency and its invariance over time. Results: The gender distribution of the sample was found to be 61.3% female and 38.7% male. According to the results of EFA, items 8 and 18 were removed from the Turkish-adapted version. As a result of the reliability analysis conducted with the Turkish version of the scale, the Cronbach alpha coefficient was obtained as 0.851 for the post-pandemic health promotion behavior. Additionally, the scale was rated as reliable with the following Cronbach alpha values: 0.79 for the personal hygiene, 0.78 for dietary habits, 0.72 for using mobile devices, 0.70 for emotional health, 0.68 for health care and physical activity, and 0.51 for social health sub-dimensions. To examine the six sub-dimension factor structures of the scale, fit indices were calculated as chi 2/df (1.722), GFI (0.894), IFI (0.908), TLI (0.892), CFI (0.907), RMSEA (0.048), and SRMR (0.057) and were within acceptable limits. Findings of the multi-group confirmatory factor analysis for measurement invariance were less than or equal to 0.01 for the triangle CFI and triangle RMSEA values across all indices. Consequently, it was observed that the item-factor structure, factor loadings, variances, covariances, and error variances of the scale were equivalent for both male and female young adults, while test-retest results showed a high positive correlation. Conclusions: The Turkish version of the post-pandemic health promotion behavior scale of young adults in the digital age scale, consisting of 25 items and six subscales, was proven to be a valid and reliable tool to measure health promotion behavior in young adults aged 19-29 years.Article Citation - WoS: 2Citation - Scopus: 2Adrenal Lesion Classification With Abdomen Caps and the Effect of Roi Size(Springer, 2023) Solak, Ahmet; Ceylan, Rahime; Bozkurt, Mustafa Alper; Cebeci, Hakan; Koplay, MustafaAccurate classification of adrenal lesions on magnetic resonance (MR) images are very important for diagnosis and treatment planning. The detection and classification of lesions in medical imaging heavily rely on several key factors, including the specialist's level of experience, work intensity, and fatigue of the clinician. These factors are critical determinants of the accuracy and effectiveness of the diagnostic process, which in turn has a direct impact on patient health outcomes. With the spread of artificial intelligence, the use of computer-aided diagnosis (CAD) systems in disease diagnosis has also increased. In this study, adrenal lesion classification was performed using deep learning on MR images. The data set used was obtained from the Department of Radiology, Faculty of Medicine, Selcuk University, and all adrenal lesions were identified and reviewed in consensus by two radiologists experienced with abdominal MR. Studies were carried out on two different data sets created by T1- and T2-weighted MR images. The data set consisted of 112 benign and 10 malignant lesions for each mode. Experiments were performed with regions of interest (ROIs) of different sizes to increase the working performance. Thus, the effect of the selected ROI size on the classification performance was assessed. In addition, instead of the convolutional neural network (CNN) models used in deep learning, a unique classification model structure called Abdomen Caps was proposed. When the data sets used in classification studies are manually separated for training, validation, and testing, different results are obtained with different data sets for each stage. To eliminate this imbalance, tenfold cross-validation was used in this study. The best results obtained were 0.982, 0.999, 0.969, 0.983, 0.998, and 0.964 for accuracy, precision, recall, F1-score, area under the curve (AUC) score, and kappa score, respectively.Article Citation - WoS: 2Citation - Scopus: 3Alternative Green Application Areas for Olive Pomace Catalytic Pyrolysis Biochar Obtained Via Marble Sludge Catalyst(Springer, 2024) Göktepeli, Gamze; Özgan, Afra; Önen, Vildan; Ahmetli, Gülnare; Kalem, Merve; Yel, EsraEvaluating industrial wastes in the system with minimum preprocessing and generation economically valuable products from them have critical importance. In this regard, especially cheap, wieldy, and readily available catalysts have been researched to increase variety of useful products in pyrolysis systems, to reduce process time, and to increase quality and diversity of products. Therefore, in this study, marble sludge (named K1) was evaluated as catalyst at different dosages (10%, 20%, 30%, 50%) and pyrolysis temperatures (300, 500, 700 degrees C) in olive pomace (OP) pyrolysis and; the potential green applications of produced new biochars at new usage areas with different purposes based on characteristics were investigated. ANOVA test results showed that temperature and catalysts ratio had significant effect on pyrolysis product yields since significance value for K1 and temperature was lower than 0.05 for pyrolysis products. OP-K1 biochars had alkaline properties and high earth metal quantities. Moreover, increment in K1 ratio and temperature resulted in decrement of the biochar surface acidity. Therefore, it can be indicated that these biochars can have a potential usage for anaerobic digestion processes, lithium-ion batteries, and direct carbon solid oxide fuel cell (DC-SOFC) but further electrochemical property test should be performed. Moreover, produced biochars can be alternative fuels in some processes instead of coal since they have low S content and high heat values. Consequently, it is foreseen that produced biochars will have an important place in the development of potential usage areas with a new and environmentally friendly approach in different areas apart from the conventional uses of catalytic pyrolysis chars.Article Citation - WoS: 1Citation - Scopus: 1Analysis of Fluid Forces Impacting on the Impeller of a Mixed Flow Blood Pump With Computational Fluid Dynamics(Sage Publications Ltd, 2024) Diallo, Abdoulaye Billo; Cinar, Hasan; Yapici, RafetThis study presents four different impeller designs to compare hydrodynamic forces. Numerical simulation studies are performed via computational fluid dynamics to specify and investigate the hydraulic forces impacting the impeller of the mixed-flow blood pump with a volute. The design point of this pump is that the flow rate is 5 L/min, the rotational speed is 8000 rpm, and the manometric head is 100 mmHg. The designed impellers are placed in the same volute and simulation studies are performed with the same mesh size (17.3 million cells) of the pumps. The simulation studies have been conducted in setting 1050 kg/m3 blood density, 35 cP fluid viscosity, and SST-k omega turbulence model. Additionally, this study examines the changes in hydraulic forces and hydraulic efficiency with fluid viscosity. As a result of experimental simulation studies, the highest hydraulic efficiencies of 40.87% and 39.5% are achieved in the case of the shaftless-grooveless and shafted-grooveless impeller, respectively. The maximum axial forces are obtained from the pump with the shaftless-grooveless impeller. Whereas radial forces, maximum values are calculated in the pump with the shaftless-outer groove impeller for all flow rates. Finally, the wall shear stresses, which are important for blood pump designs, are evaluated and the maximum value of 227 Pa is observed in the pump impeller with a shaftless-grooved.Erratum Citation - WoS: 3Citation - Scopus: 14Author Correction: a Portrait of the Higgs Boson by the Cms Experiment Ten Years After the Discovery (nature, (2022), 607, 7917, (60-68), 10.1038/S41586-022-04892-x)(Nature Research, 2023) Tumasyan A.; Adam W.; Andrejkovic J.W.; Bergauer T.; Chatterjee S.; Damanakis K.; Dragicevic M.; Gürpınar Güler, Emine; Güler, YalçınCorrection to: Nature Published online 4 July 2022 In the version of this article initially published, CMS Collaboration author names, affiliations and acknowledgements were omitted and have now been included in the HTML and PDF versions of the article. © 2023, The Author(s).Article Citation - WoS: 1Citation - Scopus: 1Bacterial Microbiome Diversity Along Poultry Slaughtering Lines: Insights From Chicken Carcasses and Environmental Sources(Sciendo, 2024) Telli, Arife Ezgi; Bicer, Yusuf; Telli, Nihat; Sönmez, Gonca; Turkal, Gamze; Güzel, İsmailIntroduction This study aimed to determine the bacterial diversity of chicken carcasses and their surrounding environment at various stages along a poultry slaughter line.Material and Methods Amplicon sequencing of the 16S rRNA gene was employed to assess the shifts in bacterial community diversity at both phylum and genus levels. Samples were collected from September to November 2021, targeting carcass surfaces at various operational stages (post-defeathering, post-evisceration, post-water chilling, and post-cooling), as well as from the internal environments and air of these units. The study took place in a vertically integrated poultry slaughterhouse in Konya, Turkey.Results Microbial diversity increased after the chilling and storage stages as a result of redistribution of the microorganisms after the physical effect of the slaughtering stages. The final product sample taken after storage had the highest bacterial abundance. The abundance at this stage was found to be strongly correlated with that at other slaughtering stages, as well as with the abundance in chilling water and on the personnel's hands. The common genera in chicken carcasses during slaughter stages were Macrococcus, Acinetobacter, Enterococcus, Escherichia-Shigella, Psychrobacter, Streptococcus, Lactococcus and Ligilactobacillus. Microbiome data in environmental samples indicated that the genera in highest relative abundance were Bacillus, Anoxybacillus, Acinetobacter and Psychrobacter. In air samples, the storage room had the highest diversity and in this place Bacillus spp. and Staphylococcus spp. were in the majority.Conclusion This study may provide some useful information to pinpoint the critical contamination sources in the poultry slaughtering process.Article Citation - WoS: 12Citation - Scopus: 15Biopolymeric Nanofibrous Scaffolds of Poly(3-hydroxybuthyrate)/Chitosan Loaded With Biogenic Silver Nanoparticle Synthesized Using Curcumin and Their Antibacterial Activities(Elsevier B.V., 2024) Bayram, Sarıipek, F.The increasing prevalence of multi-drug resistant bacteria poses a significant threat to public health, especially in wound infections. Developing new bactericidal agents and treatment strategies is crucial to address this issue. In this study, biopolymeric nanofibrous scaffolds containing green-synthesized silver nanoparticles (AgNPs) with curcumin (CUR) were evaluated as antimicrobial materials for wound healing therapy. Firstly, CUR was utilized to synthesize AgNPs, which were then analyzed using various analytical methods. The microstructural analysis revealed that the biogenic AgNPs, which had a spherical shape and an average size of 19.83 nm, were uniformly anchored on PHB/CTS nanofibers. Then, the AgNPs with various content (0.25–1%wt) were incorporated into PHB/CTS matrix to enhance its wettability, thermal and bactericidal behaviors. The nanofibrous scaffolds were characterized by FT-IR, FE-SEM, TGA analysis and water contact angle measurement. Overall, the addition of CUR-AgNPs to the PHB/CTS matrix led to a reduction in fiber diameter, enhanced hydrophilicity and improved thermal properties. Additionally, antibacterial activity against Staphylococcus aureus and Escherichia coli was performed on samples of AgNPS and PHB/CTS/CUR-Ag. The synthesized AgNPs showed antibacterial activity against both microorganisms, especially against S. aureus. Higher concentrations of AgNPs in nanofibers led to a significant reduction in bacterial colony formation. The results displayed that PHB/CTS/CUR-AgNPs nanofibrous scaffolds could be a promising material for the biomedical applications such as wound healing. © 2023 Elsevier B.V.Article Citation - WoS: 36Citation - Scopus: 40Buckling Analysis of Cnt-Reinforced Polymer Composite Beam Using Experimental and Analytical Methods(MDPI, 2023) Madenci, Emrah; Özkılıç, Yasin Onuralp; Aksoylu, Ceyhun; Asyraf, Muhammad Rizal Muhammad; Syamsir, Agusril; Supian, Abu Bakar Mohd; Mamaev, NicolayThe aim of this article was to investigate the effect of carbon nanotubes (CNTs) on the buckling behavior of fiber-reinforced polymer (FRP) composites. The materials used included three layers: carbon-fiber-reinforced polymer (CFRP), epoxy and CNTs. A set of mechanical tests, such as compression and buckling tests, was performed, and also analytical solutions were developed. Damage analysis was also carried out by controlling the damage initiation and crack progression on the composite samples. Experimental results revealed that using 0.3% with CNT additives enhanced the buckling performance of the composite. Finally, the average load-carrying capacity for the clamped-clamped boundary condition was 268% higher in the CNT samples and 282% higher in the NEAT samples compared to the simple-simple condition.Article Citation - WoS: 2Citation - Scopus: 2Calixarene-Based Functional Fabric for Simultaneously Adsorptive Removal of Anionic and Cationic Dyes(Amer Chemical Soc, 2025) Ozcelik, Egemen; Tabakci, Begum; Karaman, Mustafa; Tabakci, MustafaThis study investigated the adsorptive properties of functionalized fabric containing dimethylaminomethyl calix[4]arene (DMAM-Calix) to remove anionic methyl orange (MO) and cationic Rhodamine B (RhB) dyes in aqueous media. Adsorption studies were performed using a filtration system packed with DMAM-Calix-functionalized fabric (DCF). The results revealed that the cationic and anionic structures work compatibly in a binary mixture medium. Hydrogen bonding, pi-pi, cation-pi, n-pi and electrostatic interactions between dye molecules and DMAM-Calix units of DCF were the main factors affecting the adsorption process. Experiments on real wastewater samples of unknown composition confirmed that the approach could successfully remove MO and RhB dyes from real water samples with high efficiency, especially for RhB. Isotherm and kinetic data for MO were mainly represented by the Langmuir model and pseudo-second-order kinetic model, respectively. The adsorption capacities of DCF were found to be about 4.7 mg g-1 for MO and 1.0 mg g-1 for RhB at pH 6.0, which were evaluated as satisfactory considering the first use of a calixarene-derived coated fabric as an adsorbent, the anionic-cationic dye selectivity of DCF, and the low cost and ease of application of the method.Article Carbon Nanotube-Supported Bimetallic Core-Shell (m@pd/Cnt (m: Zn, Mn, Ag, Co, V, Ni)) Cathode Catalysts for H2o2 Fuel Cells(AMER CHEMICAL SOC, 2023) Yapıcı, Burak; Gökdoğan Şahin, ÖzlemM@Pd/CNT (M: Zn, Mn, Ag, Co, V, Ni) core-shell and Pd/CNT nanoparticles were prepared by sodium borohydride reduction and explored as cathode catalysts for the hydrogen peroxide reduction reaction. Electrochemical and physical characterization techniques are applied to explore the characteristics of the produced electrocatalysts. The cyclic voltammetry (CV) experiments show that Zn@Pd/CNT-modified electrodes have a current density of 273.2 mA cm(-2), which is 3.95 times higher than that of Pd/CNT. According to the chronoamperometric curves, Zn@Pd/CNT has the highest steady-state current density for the H2O2 electro-reduction process among the synthesized electrocatalysts. Moreover, electrochemical impedance spectroscopy (EIS) spectra confirmed the previous electrochemical results due to the lowest charge transfer resistance (35 Omega) with respect to other electrocatalysts.Article Citation - WoS: 5Citation - Scopus: 5Catalytic Effect of Nickel Oxide Nanoparticles From Lupinus Albus Extract on Green Synthesis and Photocatalytic Reduction of Methylene Blue: Kinetics and Mechanism(Taylor & Francis Inc, 2024) Yılmaz, Mine; Ceyhan, A. Abdullah; Baytar, OrhanGreen synthesis of nanomaterials is advancing due to their ease of synthesis, cheapness, nontoxicity, and renewability. An environmentally friendly biogenic method has been developed for the green synthesis of nickel oxide nanoparticles (NiO NPs) using phytochemical-rich bioextract. They are rich in bioextract phenolics, flavonoids, and berberine. These phytochemicals successfully reduce and stabilize NiNO3 into NiO NPs. In this study, NiO NPs were synthesized by the green synthesis method from Lupinus Albus. Characterization of NiO NPs was carried out by TEM, XRD, SEM, UV, XRF, BET, and EDX analyses. According to XRD analysis, TEM results also support this, where the NiO NPs particle size diameter is 5 nm. It was determined by the Tauc equation that the band energy gap of NiO NPs is 1.69 eV. It was determined that the BET surface area of NiO NPs was 49.6 m2/g. NiO nanoparticles synthesized from Lupinus Albus extract by the green synthesis method were used as catalysts in the photocatalytic reduction of methylene blue with NaBH4. In the photocatalytic reduction of methylene blue with NaBH4, it was determined that there was no color change in 48 h without a catalyst, and in the presence of NiO nanoparticle catalyst, methylene blue was reduced by 97% in 8 min. The kinetics of the photocatalytic reduction of methylene blue with NaBH4 is a pseudo-first-order kinetic model and the kinetic rate constant is determined as 0.66 min-1, indicating that the catalytic effect of NiO NPs is very high at this value. NiO NPs were used five times in the photocatalytic reduction of methylene blue with NaBH4 and it was determined that the reduction of methylene blue was over 90% in each use. NiO nanoparticles were synthesized from Lupinus Albus extract by green synthesis, which is an easily applied, cost-effective, and environmentally friendly method. The synthesized NiO nanoparticles were characterized using various characterization techniques. NiO nanoparticles have a high catalytic effect in the photocatalytic reduction of methylene blue with NaBH4. Photocatalytic reduction of methylene blue with uncatalyzed NaBH4 could not be achieved, and 97% reduction of methylene blue was completed in 8 min in the presence of NiO nanoparticle catalyst.Article Citation - WoS: 12Citation - Scopus: 16Characterization of Polysaccharide Extracts of Four Edible Mushrooms and Determination of in Vitro Antioxidant, Enzyme Inhibition and Anticancer Activities(Amer Chemical Soc, 2024) Deveci, Ebru; Tel-Cayan, Gülsen; Cayan, Fatih; Altinok, Bahar Yilmaz; Aktaş, SinanMushroom polysaccharides are important bioactive compounds derived from mushrooms with various beneficial properties. In this study, the chemical characterization and bioactivities of polysaccharide extracts from four different edible mushrooms, Clavariadelphus truncatus Donk, Craterellus tubaeformis (Fr.) Quel., Hygrophorus pudorinus (Fr.) Fr., and Macrolepiota procera (Scop.) Singer were studied. Glucose (13.24-56.02%), galactose (14.18-64.05%), mannose (2.18-18.13%), fucose (1.21-5.78%), and arabinose (0.04-5.43%) were identified in all polysaccharide extracts by GC-MS (gas chromatography-mass spectrometry). FT-IR (Fourier transform infrared spectroscopy) confirmed the presence of characteristic carbohydrate patterns. H-1 NMR suggested that all polysaccharide extracts had alpha- and beta-d-mannopyranose, d-glucopyranose, d-galactopyranose, alpha-l-arabinofuranose, and alpha-l-fucopyranose residues. Approximate molecular weights of polysaccharide extracts were determined by HPLC (high-performance liquid chromatography). The best antioxidant activity was found in M. procera polysaccharide extract in DPPH center dot (1,1-diphenyl-2-picrylhydrazyl) scavenging (39.03% at 800 mu g/mL), CUPRAC (cupric reducing antioxidant capacity) (A(0.50): 387.50 mu g/mL), and PRAP (phosphomolybdenum reducing antioxidant power) (A(0.50): 384.08 mu g/mL) assays. C. truncatus polysaccharide extract showed the highest antioxidant activity in ABTS(center dot+) scavenging (IC50: 734.09 mu g/mL), beta-carotene-linoleic acid (IC50: 472.16 mu g/mL), and iron chelating (IC50: 180.35 mu g/mL) assays. Significant anticancer activity was found in C. truncatus polysaccharide extract on HT-29 (IC50: 46.49 mu g/mL) and HepG2 (IC50: 48.50 mu g/mL) cell lines and H. pudorinus polysaccharide extract on the HeLa cell line (IC50: 51.64 mu g/mL). Also, H. pudorinus polysaccharide extract possessed prominent AChE (acetylcholinesterase) inhibition activity (49.14% at 200 mu g/mL).Article Citation - Scopus: 1Co-Flotation of Effluents From Detergent and Marble Processing Industries in Denver and Dispersed Air Flotation Systems(Elsevier Ltd, 2024) Yel, E.; Onen, V.; Kalem, M.Suspended solids in the marble processing wastewater (MPWW) have the potential to pollute receiving media. Likewise, detergent production wastewater (DPWW) needs treatment prior to discharge as they include surfactants and others. Flotation and its modifications are common for separation purposes in various engineering solutions. To increase flotation performance by changing the surface tension some collector and frother chemicals, surfactants are utilized. Detergents are among important surfactants and they may act as both frother and collector in flotation. Therefore, the purpose of this study was to determine the effectiveness of DPWW in co-flotation with MPWW. Two effluents were mixed at varying ratios and dispersed air (DISP) and Denver (DEN) flotation co-treatment were applied to the mixtures. Volume ratio, time and air flow rate on treatment performance were investigated. Turbidity, solids, COD, phosphate removals were achieved at varying levels when the flotation was applied to the mixture. The highest treatment performance was achieved at 90%MPWW-10%DPWW mixture. 10 min flotation time and 2 L min−1 air flow rate for the DEN system, and 20 min and 6 L min−1 for the DISP system were recommended. Under these conditions turbidity, SS, COD, phosphate and alkalinity residuals (and removal efficiencies) were 2400 NTU(82%), 1720 mg.L−1(89%), 313.6 mg.L−1(10%), 20 mg.L−1(20%) and 600 mg.L−1CaCO3(92%) in the DEN system, respectively. Whereas, in the DISP system, under the same conditions, final values of 1880 NTU(86%), 1540 mg.L−1(91%), 262 mg.L−1(17%), 21 mg.L−1(20%) and 470 mg.L−1(94%) were obtained, respectively. The highest SludgeSS concentration increased up to 19300 mg.L−1 in the 90%–10% mixture. In all samples, dewaterable sludge was obtained. By this study, co-flotation of these two effluents was recommended. Within SDGs, this approach will replace frother chemical usage. The process performance can further be enhanced via flotation modifications and technology can be developed as further study. © 2024 Elsevier LtdArticle Citation - WoS: 5Citation - Scopus: 5Combined Use of Bwm-Topsis Methods in the Selection of Thermal Power Plant Installation Site in the Karapinar/Turkiye Region, at Risk of Sinkhole Formation(Springer Science and Business Media Deutschland GmbH, 2024) Gumussoy, A.D.; Onen, V.; Yalpir, S.With the rapidly increasing world population and the need for industrialization, energy supply has become an important global problem. A significant part of the world's energy needs is provided by fossil fuels. About half of all global coal deposits are low-quality coals, including lignite. Karapınar/Konya, also the study area, has Turkiye's second richest lignite reserve. The region's lignite reserve can be used in thermal power plants for electricity generation in terms of its nature and the amount is an important opportunity to meet the energy demand for both region and country. The region contains many sinkholes, and the potential for the formation of new sinkholes makes the site selection for thermal power plants in the region an even more strategic decision. This study aims to propose the most suitable thermal power plant site for the region by using Multi-Criteria Decision Making methods and Geographic Information Systems in an integrated way. Within the scope of the study, a total of twelve sub-criteria were taken into consideration under the main criteria of Geological, Economic and Environmental. The Best–Worst Method was applied to determine the criteria weights, and by using the weights, a suitability map for the thermal power plant installation site was produced and candidate regions were determined. TOPSIS was applied to determine the most suitable location among the candidate regions. The Candidate Region in the easternmost part of Karapinar district was chosen as the most suitable site for the thermal power plant installation. © 2023, The Author(s), under exclusive licence to Springer Nature Switzerland AG.Article Citation - WoS: 1Citation - Scopus: 2Computational Fluid Dynamics Simulating of the Fda Benchmark Blood Pump With Different Coefficient Sets and Scaler Shear Stress Models Used in the Power-Law Hemolysis Model(Springer Japan Kk, 2025) Önder, Ahmet; İncebay, Ömer; Yapıcı, RafetHemolysis is the most important issue to consider in the design and optimization of blood-contacting devices. Although the use of Computational Fluid Dynamics (CFD) in hemolysis prediction studies provides convenience and has promising potential, it is an extremely challenging process. Hemolysis predictions with CFD depend on the mesh, implementation method, coefficient set, and scalar-shear-stress model. To this end, an attempt was made to find the combination that would provide the most accurate result in hemolysis prediction with the commonly cited power-law based hemolysis model. In the hemolysis predictions conducted using CFD on the Food and Drug Administration (FDA) benchmark blood pump, 3 different scalar-shear-stress models, and 5 different coefficient sets with the power-law based hemolysis model were used. Also, a mesh independence test based on hemolysis and pressure head was performed. The pressure head results of CFD simulations were compared with published pressure head of the FDA benchmark blood pump and a good agreement was observed. In addition, results of CFD-hemolysis predictions which are conducted with scalar-shear-stress model and coefficient set combinations were compared with experimental hemolysis data at three operating conditions such as 6-7 L/min flow rates at 3500 rpm rotational speeds and 6 L/min at 2500 rpm. One of the combinations of the scalar-shear-stress model and the coefficient set was found to be within the error limits of the experimental measurements, while all other combinations overestimated hemolysis.Review Citation - WoS: 17Citation - Scopus: 20Creep Properties and Analysis of Cross Arms' Materials and Structures in Latticed Transmission Towers: Current Progress and Future Perspectives(MDPI, 2023) Asyraf, Muhammad Rizal Muhammad; Rafidah, Mazlan; Madenci, Emrah; Özkılıç, Yasin Onuralp; Aksoylu, Ceyhun; Razman, Muhammad Rizal; Ramli, ZuliskandarFibre-reinforced polymer (FRP) composites have been selected as an alternative to conventional wooden timber cross arms. The advantages of FRP composites include a high strength-to-weight ratio, lightweight, ease of production, as well as optimal mechanical performance. Since a non-conductive cross arm structure is exposed to constant loading for a very long time, creep is one of the main factors that cause structural failure. In this state, the structure experiences creep deformation, which can result in serviceability problems, stress redistribution, pre-stress loss, and the failure of structural elements. These issues can be resolved by assessing the creep trends and properties of the structure, which can forecast its serviceability and long-term mechanical performance. Hence, the principles, approaches, and characteristics of creep are used to comprehend and analyse the behaviour of wood and composite cantilever structures under long-term loads. The development of appropriate creep methods and approaches to non-conductive cross arm construction is given particular attention in this literature review, including suitable mitigation strategies such as sleeve installation, the addition of bracing systems, and the inclusion of cross arm beams in the core structure. Thus, this article delivers a state-of-the-art review of creep properties, as well as an analysis of non-conductive cross arm structures using experimental approaches. Additionally, this review highlights future developments and progress in cross arm studies.Article Citation - WoS: 3Citation - Scopus: 3Diagnosis of Covid-19 From Blood Parameters Using Convolutional Neural Network(Springer, 2023) Doğan, Gizemnur Erol; Uzbaş, BetülAsymptomatically presenting COVID-19 complicates the detection of infected individuals. Additionally, the virus changes too many genomic variants, which increases the virus's ability to spread. Because there isn't a specific treatment for COVID-19 in a short time, the essential goal is to reduce the virulence of the disease. Blood parameters, which contain essential clinical information about infectious diseases and are easy to access, have an important place in COVID-19 detection. The convolutional neural network (CNN) architecture, which is popular in image processing, produces highly successful results for COVID-19 detection models. When the literature is examined, it is seen that COVID-19 studies with CNN are generally done using lung images. In this study, one-dimensional (1D) blood parameters data were converted into two-dimensional (2D) image data after preprocessing, and COVID-19 detection was made with CNN. The t-distributed stochastic neighbor embedding method was applied to transfer the feature vectors to the 2D plane. All data were framed with convex hull and minimum bounding rectangle algorithms to obtain image data. The image data obtained by pixel mapping was presented to the developed 3-line CNN architecture. This study proposes an effective and successful model by providing a combination of low-cost and rapidly-accessible blood parameters and CNN architecture making image data processing highly successful for COVID-19 detection. Ultimately, COVID-19 detection was made with a success rate of 94.85%. This study has brought a new perspective to COVID-19 detection studies by obtaining 2D image data from 1D COVID-19 blood parameters and using CNN.Article Citation - Scopus: 2Direct or Dna Extraction-Free Amplification and Quantification of Foodborne Pathogens(2025) Williams M.R.; Telli A.E.; Telli N.; Islam D.T.; Hashsham S.A.The use of direct nucleic acid amplification of pathogens from food matrices has the potential to reduce time to results over DNA extraction-based approaches as well as traditional culture-based approaches. Here we describe protocols for assay design and experiments for direct amplification of foodborne pathogens in food sample matrices using loop-mediated isothermal amplification (LAMP) and polymerase chain reaction (PCR). The examples provided include the detection of Escherichia coli in milk samples and Salmonella in pork meat samples. This protocol includes relevant reagents and methods including obtaining target sequences, assay design, sample processing, and amplification. These methods, though used for specific example matrices, could be applied to many other foodborne pathogens and sample types. © 2025. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.Article Citation - WoS: 33Citation - Scopus: 41Dissemination of Nonsteroidal Anti-Inflammatory Drugs (nsaids) and Metabolites From Wastewater Treatment Plant To Soils and Agricultural Crops Via Real-Scale Different Agronomic Practices(Academic Press Inc Elsevier Science, 2023) Dolu, Taylan; Nas, BilgehanOne of the most consumed pharmaceutical subgroups across the world is nonsteroidal anti-inflammatory drugs (NSAIDs). However, the dissemination of these compounds to the natural environments through agronomic practices is a serious global problem. The hypothesis of this study is to reveal the transition of selected NSAIDs, paracetamol (PAR), diclofenac (DCF), ibuprofen (IBU), and naproxen (NAP) together with six main metabolites, detected in raw/treated wastewater (RWW/TWW) and sewage sludge generated in an urban wastewater treat-ment plant (WWTP) to soils and agricultural crops (corn, barley, sunflower, and sugar beet) through two widely applied agronomic practices, irrigation with TWW and application of sewage sludge as soil amendment. In other words, the cycles of 10 NSAIDs have been evaluated by simultaneously monitoring their concentrations in RWW/ TWW, sewage sludge, soils, and crops. It was determined that the parent compounds and detected metabolites were treated at quite higher removal efficiencies (93.4 - >99.9%) in the studied WWTP, while DCF was elim-inated poorly (7.9-52.2%). However, although it changes seasonally for some compounds, it was determined that the concentrations of almost all investigated NSAIDs increased at the determined irrigation points in the discharge channel (DC) where agricultural irrigations were performed. Apart from that, DCF, NAP, and 2-hydroxyibuprofen (2-OH-IBU) were always detected in sewage sludge seasonally up to about 20.5, 11.3, and 3.7 ng/g, respectively. While 2-OH-IBU was determined as the dominant metabolite in RWW, TWW, and sewage sludge, the metabolite of 1-hydroxyibuprofen (1-OH-IBU) was determined as the dominant compound in soils. Although 1-OH-IBU was not detected in TWW and sewage sludge in any season, detecting this metabolite as a common compound in all investigated soils (up to 60.1 ng/kg) reveals that this compound is the primary transformation product of IBU in soils. It was observed that at least one of the metabolites of IBU (1-OH-IBU and/ or 2-OH-IBU) was detected in all plants grown (up to 0.75 ng/g), especially during the periods when both agricultural practices were applied. In addition, the detection of 1-OH-IBU with increasing concentrations from root to shoots in corn grown as a result of both agronomic practices shows that this compound has a high translocation potential in the corn plant. Apart from this, it was determined that PAR was detected in corn (up to 43.3 ng/kg) and barley (up to 16.8 ng/kg) within the scope of irrigation with TWW, and NAP was detected in sugar beet (up to 11.2 ng/kg) through sewage sludge application.Article Citation - WoS: 5Citation - Scopus: 5Effective Isolation of Succinic Acid From Aqueous Media With the Use of Anion Exchange Resins(Royal Soc Chemistry, 2024) Asım, Hamayoun; Zeidan, Hani; Marti, Mustafa EsenThe primary objective of this study was to examine the isolation of succinic acid (SA) from aqueous-based solutions through the utilization of adsorption and ion exchange methods. Four kinds of anion exchange resins were employed, two of which were strong basic (Lewatit M-500 and Lewatit M-600), and the other two were weak basic (Lewatit MP-64 and Lewatit MP-62). The impacts of various variables on the efficiency of the process were examined. The aqueous pH strongly influenced the separation yield. Weak basic exchangers achieved the maximum yield at pH 2.1. However, the highest performance with Lewatit M-600 and Lewatit M-500 was obtained at pH 5 and 6, respectively. The SA separation with the tested resins reached equilibrium in about an hour. The recovery data revealed consistency with the Langmuir isotherm and pseudo-second-order kinetics. Efficiency improved with resin dosage and reduced with SA concentration. It was found that weak basic anion exchange resins were more efficient than strong basic exchangers for the recovery process. Among the resins tested, Lewatit MP-62 demonstrated the highest sorption capacity of 321 mg g-1 and 97.5% yield. The performance of the system decreased with temperature for all alternatives tested; however, its impact was not notable. The isolation process had an exergonic, exothermic, and favorable character based on the thermodynamic constants. Acid-loaded resins were successfully regenerated using trimethylamine and HCl for weak and strong anion exchange resins, respectively. Succinic acid recovery using weak basic anion (WBA) and strong basic anion (SBA) exchange resins.

