Computational Fluid Dynamics Simulating of the Fda Benchmark Blood Pump With Different Coefficient Sets and Scaler Shear Stress Models Used in the Power-Law Hemolysis Model
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Date
2025
Authors
Önder, Ahmet
İncebay, Ömer
Yapıcı, Rafet
Journal Title
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Volume Title
Publisher
Springer Japan Kk
Open Access Color
Green Open Access
No
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Publicly Funded
No
Abstract
Hemolysis is the most important issue to consider in the design and optimization of blood-contacting devices. Although the use of Computational Fluid Dynamics (CFD) in hemolysis prediction studies provides convenience and has promising potential, it is an extremely challenging process. Hemolysis predictions with CFD depend on the mesh, implementation method, coefficient set, and scalar-shear-stress model. To this end, an attempt was made to find the combination that would provide the most accurate result in hemolysis prediction with the commonly cited power-law based hemolysis model. In the hemolysis predictions conducted using CFD on the Food and Drug Administration (FDA) benchmark blood pump, 3 different scalar-shear-stress models, and 5 different coefficient sets with the power-law based hemolysis model were used. Also, a mesh independence test based on hemolysis and pressure head was performed. The pressure head results of CFD simulations were compared with published pressure head of the FDA benchmark blood pump and a good agreement was observed. In addition, results of CFD-hemolysis predictions which are conducted with scalar-shear-stress model and coefficient set combinations were compared with experimental hemolysis data at three operating conditions such as 6-7 L/min flow rates at 3500 rpm rotational speeds and 6 L/min at 2500 rpm. One of the combinations of the scalar-shear-stress model and the coefficient set was found to be within the error limits of the experimental measurements, while all other combinations overestimated hemolysis.
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ORCID
Keywords
Centrifugal blood pump, CFD, Hemolysis, Scalar shear stress, Mechanical Hemolysis, Flow, Prediction, Performance, United States Food and Drug Administration, Hydrodynamics, Models, Cardiovascular, Humans, Computer Simulation, Stress, Mechanical, Heart-Assist Devices, Equipment Design, Hemolysis, United States
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WoS Q
Q3
Scopus Q
Q3

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N/A
Source
Journal of Artificial Organs
Volume
28
Issue
Start Page
184
End Page
191
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CrossRef : 1
Scopus : 3
PubMed : 1
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1.10257789
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3
GOOD HEALTH AND WELL-BEING

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