01. Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed

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    Citation - WoS: 12
    Citation - Scopus: 15
    Biopolymeric Nanofibrous Scaffolds of Poly(3-hydroxybuthyrate)/Chitosan Loaded With Biogenic Silver Nanoparticle Synthesized Using Curcumin and Their Antibacterial Activities
    (Elsevier B.V., 2024) Bayram, Sarıipek, F.
    The increasing prevalence of multi-drug resistant bacteria poses a significant threat to public health, especially in wound infections. Developing new bactericidal agents and treatment strategies is crucial to address this issue. In this study, biopolymeric nanofibrous scaffolds containing green-synthesized silver nanoparticles (AgNPs) with curcumin (CUR) were evaluated as antimicrobial materials for wound healing therapy. Firstly, CUR was utilized to synthesize AgNPs, which were then analyzed using various analytical methods. The microstructural analysis revealed that the biogenic AgNPs, which had a spherical shape and an average size of 19.83 nm, were uniformly anchored on PHB/CTS nanofibers. Then, the AgNPs with various content (0.25–1%wt) were incorporated into PHB/CTS matrix to enhance its wettability, thermal and bactericidal behaviors. The nanofibrous scaffolds were characterized by FT-IR, FE-SEM, TGA analysis and water contact angle measurement. Overall, the addition of CUR-AgNPs to the PHB/CTS matrix led to a reduction in fiber diameter, enhanced hydrophilicity and improved thermal properties. Additionally, antibacterial activity against Staphylococcus aureus and Escherichia coli was performed on samples of AgNPS and PHB/CTS/CUR-Ag. The synthesized AgNPs showed antibacterial activity against both microorganisms, especially against S. aureus. Higher concentrations of AgNPs in nanofibers led to a significant reduction in bacterial colony formation. The results displayed that PHB/CTS/CUR-AgNPs nanofibrous scaffolds could be a promising material for the biomedical applications such as wound healing. © 2023 Elsevier B.V.
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    Citation - WoS: 5
    Citation - Scopus: 4
    Modal and Random Vibration Responses of Composite Overwrapped Pressure Vessels With Various Geodesic Dome Trajectories
    (SAGE Publications Ltd, 2025) Coskun, T.; Sahin, O.S.
    In the current study, Composite Overwrapped Pressure Vessels (COPVs) with various geodesic dome profiles have been built and their modal and random vibration responses were numerically examined. In this regard, geodesic dome profiles were established for five different polar opening radii of 10, 15, 20, 25, and 30 mm, and thus the impacts of fibre orientations on vibration characteristics depending on the filament winding trajectories were discovered. Furthermore, non-prestressed modal and random vibration responses for COPVs, as well as prestressed vibration behaviours under 50, 100, and 150 Bar internal pressure, were investigated and thus the effects of internal pressure severity on dynamic characteristics were identified. The study found that higher polar opening radius triggered a reduction in the natural frequencies, and these reductions were linked to an increment in the filament winding angle, and a consequent deterioration in the structural stiffness of COPVs. On the other hand, raising the internal pressure severity shifts the natural frequencies to higher frequencies, which are also attributed to ascended structural stiffness. Furthermore, it was established that internal pressure severity and polar opening radius had a coupled effects on the modal and random responses, and that both parameters should be evaluated simultaneously. © The Author(s) 2024.