Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections
Permanent URI for this collectionhttps://hdl.handle.net/20.500.13091/3
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Browsing Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections by Department "Enstitüler, Lisansüstü Eğitim Enstitüsü, Endüstri Mühendisliği Ana Bilim Dalı"
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Article Reducing the Impact of Cutaneous Leishmaniasis Disease by Domestic Animals and Tilapia Fish: a System Dynamics Model(2019) Kurt, Şeyma; Kesen, Saadettin ErhanThe purpose of this paper is to seek ways in reducing incidence of vector borne disease called leishmaniasis on humans. Frequently encountered in East Mediterranean and Southeastern Anatolian region of Turkey due to risk factors including poverty, malnutrition, lack of sanitation and defrostration, leishmaniasis disease is transmitted by sandflies’ (vector) bites to humans. In addition to the zooprophylaxis effect in which domestic animals acting as dead-end hosts are used to alleviate the incidence on humans, we also incorporate the Tilapia fish population into the model to observe its effect in terms of relieving the vector bites on humans. We elaborate dynamic behavior and feedback loop structure of the system under study with three blood meal hosts: rodents, humans, and domestic animals. Proposed model is simulated throughout a period of 1000 days. We conduct sensitivity analysis by changing the rates of vector biting and the number of larvae eaten by Tilapia fish which influence the transmission of the disease. Results indicate that basic reproductive number ??0 and its prevalence in humans decreases as the size of domestic animal and the sandflies larvae eaten by Tilapia fish increases.

