Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.13091/6397
Title: | Electrochemical Detection of Nucleic Acids Using Three-Dimensional Graphene Screen-Printed Electrodes | Authors: | Islam D.T. Mobasser S. Kotaru S. Telli A.E. Telli N. Cupples A.M. Hashsham S.A. |
Keywords: | Biomarkers Electrochemistry Hybridization Screen-printed electrodes Three dimensional graphene Biosensing Techniques DNA Electrochemical Techniques Electrodes Graphite Humans Nucleic Acids DNA graphite nucleic acid chemistry devices electrochemical analysis electrode genetic procedures human procedures |
Abstract: | Electrochemical approaches, along with miniaturization of electrodes, are increasingly being employed to detect and quantify nucleic acid biomarkers. Miniaturization of the electrodes is achieved through the use of screen-printed electrodes (SPEs), which consist of one to a few dozen sets of electrodes, or by utilizing printed circuit boards. Electrode materials used in SPEs include glassy carbon (Chiang H-C, Wang Y, Zhang Q, Levon K, Biosensors (Basel) 9:2-11, 2019), platinum, carbon, and graphene (Cheng FF, He TT, Miao HT, Shi JJ, Jiang LP, Zhu JJ, ACS Appl Mater Interfaces 7:2979-2985, 2015). There are numerous modifications to the electrode surfaces as well (Cheng FF, He TT, Miao HT, Shi JJ, Jiang LP, Zhu JJ, ACS Appl Mater Interfaces 7:2979-2985, 2015). These approaches offer distinct advantages, primarily due to their demonstrated superior limit of detection without amplification. Using the SPEs and potentiostats, we can detect cells, proteins, DNA, and RNA concentrations in the nanomolar (nM) to attomolar (aM) range. The focus of this chapter is to describe the basic approach adopted for the use of SPEs for nucleic acid measurement. © 2025. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature. | URI: | https://doi.org/10.1007/978-1-0716-4100-2_4 https://hdl.handle.net/20.500.13091/6397 |
ISSN: | 1940-6029 |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collections Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections |
Show full item record
CORE Recommender
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.