Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.13091/4945
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bayram, Sarıipek, F. | - |
dc.date.accessioned | 2023-12-26T07:52:34Z | - |
dc.date.available | 2023-12-26T07:52:34Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 0141-8130 | - |
dc.identifier.uri | https://doi.org/10.1016/j.ijbiomac.2023.128330 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.13091/4945 | - |
dc.description.abstract | The increasing prevalence of multi-drug resistant bacteria poses a significant threat to public health, especially in wound infections. Developing new bactericidal agents and treatment strategies is crucial to address this issue. In this study, biopolymeric nanofibrous scaffolds containing green-synthesized silver nanoparticles (AgNPs) with curcumin (CUR) were evaluated as antimicrobial materials for wound healing therapy. Firstly, CUR was utilized to synthesize AgNPs, which were then analyzed using various analytical methods. The microstructural analysis revealed that the biogenic AgNPs, which had a spherical shape and an average size of 19.83 nm, were uniformly anchored on PHB/CTS nanofibers. Then, the AgNPs with various content (0.25–1%wt) were incorporated into PHB/CTS matrix to enhance its wettability, thermal and bactericidal behaviors. The nanofibrous scaffolds were characterized by FT-IR, FE-SEM, TGA analysis and water contact angle measurement. Overall, the addition of CUR-AgNPs to the PHB/CTS matrix led to a reduction in fiber diameter, enhanced hydrophilicity and improved thermal properties. Additionally, antibacterial activity against Staphylococcus aureus and Escherichia coli was performed on samples of AgNPS and PHB/CTS/CUR-Ag. The synthesized AgNPs showed antibacterial activity against both microorganisms, especially against S. aureus. Higher concentrations of AgNPs in nanofibers led to a significant reduction in bacterial colony formation. The results displayed that PHB/CTS/CUR-AgNPs nanofibrous scaffolds could be a promising material for the biomedical applications such as wound healing. © 2023 Elsevier B.V. | en_US |
dc.description.sponsorship | BAP-221016003 | en_US |
dc.description.sponsorship | The research leading to these results received funding from Scientific Research Council of Konya Technical University under Grant Agreement No. BAP-221016003 . | en_US] |
dc.description.sponsorship | The author would like to extend her heartfelt gratitude to Dr. Fatih ERCİ for his valuable contributions to the antibacterial studies conducted in this research. Additionally, the author would like to express her appreciation to the Necmettin Erbakan University Science and Technology Research and Application Center (BITAM) for providing the necessary research infrastructure. The research leading to these results received funding from Scientific Research Council of Konya Technical University under Grant Agreement No. BAP-221016003. | en_US] |
dc.language.iso | en | en_US |
dc.publisher | Elsevier B.V. | en_US |
dc.relation.ispartof | International Journal of Biological Macromolecules | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Antibacterial activity | en_US |
dc.subject | Biogenic silver nanoparticle | en_US |
dc.subject | Biopolymeric nanofibrous scaffolds | en_US |
dc.subject | Biopolymers | en_US] |
dc.subject | Contact angle | en_US] |
dc.subject | Drug delivery | en_US] |
dc.subject | Escherichia coli | en_US] |
dc.subject | Health risks | en_US] |
dc.subject | Medical applications | en_US] |
dc.subject | Metal nanoparticles | en_US] |
dc.subject | Nanofibers | en_US] |
dc.subject | Scaffolds | en_US] |
dc.subject | Scaffolds (biology) | en_US] |
dc.subject | Synthesis (chemical) | en_US] |
dc.subject | % reductions | en_US] |
dc.subject | Anti-bacterial activity | en_US] |
dc.subject | Biogenic silver nanoparticle | en_US] |
dc.subject | Biogenics | en_US] |
dc.subject | Biopolymeric nanofibrous scaffold | en_US] |
dc.subject | Curcumin | en_US] |
dc.subject | matrix | en_US] |
dc.subject | Nanofibrous scaffolds | en_US] |
dc.subject | Synthesised | en_US] |
dc.subject | Wound healing | en_US] |
dc.subject | Silver nanoparticles | en_US] |
dc.subject | biogenic silver nanoparticle | en_US] |
dc.subject | biopolymer | en_US] |
dc.subject | chitosan | en_US] |
dc.subject | chitosan nanoparticle | en_US] |
dc.subject | curcumin | en_US] |
dc.subject | nanofiber | en_US] |
dc.subject | poly(3 hydroxybutyric acid) | en_US] |
dc.subject | silver nanoparticle | en_US] |
dc.subject | unclassified drug | en_US] |
dc.subject | antibacterial activity | en_US] |
dc.subject | Article | en_US] |
dc.subject | bacterial colonization | en_US] |
dc.subject | biopolymeric nanofibrous scaffold | en_US] |
dc.subject | contact angle | en_US] |
dc.subject | controlled study | en_US] |
dc.subject | drug delivery system | en_US] |
dc.subject | Escherichia coli | en_US] |
dc.subject | field emission scanning electron microscopy | en_US] |
dc.subject | Fourier transform mass spectrometry | en_US] |
dc.subject | green chemistry | en_US] |
dc.subject | hydrophilicity | en_US] |
dc.subject | nanofabrication | en_US] |
dc.subject | nonhuman | en_US] |
dc.subject | particle size | en_US] |
dc.subject | Staphylococcus aureus | en_US] |
dc.subject | structure analysis | en_US] |
dc.subject | synthesis | en_US] |
dc.subject | thermogravimetry | en_US] |
dc.subject | transmission electron microscopy | en_US] |
dc.subject | ultraviolet visible spectrophotometry | en_US] |
dc.subject | wettability | en_US] |
dc.subject | wound healing | en_US] |
dc.subject | X ray diffraction | en_US] |
dc.title | Biopolymeric nanofibrous scaffolds of poly(3-hydroxybuthyrate)/chitosan loaded with biogenic silver nanoparticle synthesized using curcumin and their antibacterial activities | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.ijbiomac.2023.128330 | - |
dc.identifier.pmid | 38007025 | en_US |
dc.identifier.scopus | 2-s2.0-85178362906 | en_US |
dc.department | KTÜN | en_US |
dc.identifier.volume | 256 | en_US |
dc.identifier.wos | WOS:001129119000001 | en_US |
dc.institutionauthor | … | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 58736049800 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.fulltext | No Fulltext | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
Appears in Collections: | PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collections Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collections |
CORE Recommender
WEB OF SCIENCETM
Citations
1
checked on May 18, 2024
Page view(s)
62
checked on May 20, 2024
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.