Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.13091/456
Title: In vitro Antidiabetic Activity of Seven Medicinal Plants Naturally Growing in Turkey
Authors: Deveci, Ebru
Çayan, Gülsen Tel
Duru, Mehmet Emin
Abstract: Objective: Diabetes mellitus is a worldwide metabolic/endocrine disease that causes major medical problems. One of the most important strategies used in the therapy of the diabetes mellitus is the use of inhibition of ?-glucosidase and ?-amylase enzymes. Therefore, this study aimed to investigate antidiabetic activities of the hexane and methanol extracts of the medicinal plants from Turkey. Materials and Methods: The hexane and methanol extracts of Euphorbia helioscopia, Ferula elaeochytris, Sideritis albiflora, Sideritis stricta, Sideritis pisidica, Sideritis leptoclada, Salvia chionantha plants were prepared at room temperature. Antidiabetic activities of the extracts on ?-glucosidase and ?-amylase enzymes were determined. Results: S. pisidica hexane extract exhibited higher ?-amylase inhibitory activity than acarbose (96.60±0.08 %) used as a standard with an inhibition value of 97.99±0.79 % at 1000 µg/mL concentration. In terms of ?-glucosidase inhibitory activities, the extracts were ranked in the following order: F. elaeochytris hexane extract > S. leptoclada hexane extract > S. stricta hexane extract > E. helioscopia hexane extract. Conclusion: In this study, antidiabetic activities of the extracts on ?-glucosidase and ?-amylase enzymes of the studied medicinal plants were screened for the first time. It has been suggested that S. pisidica hexane extract can be used as antidiabetic agent.
URI: https://doi.org/10.26650/EurJBiol.2020.0011
https://app.trdizin.gov.tr/makale/TXpZek1qTXlNZz09
https://hdl.handle.net/20.500.13091/456
ISSN: 2602-2575
2618-6144
Appears in Collections:Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections
Teknik Bilimler Meslek Yüksekokulu Koleskiyonu
TR Dizin İndeksli Yayınlar Koleksiyonu / TR Dizin Indexed Publications Collections

Files in This Item:
File SizeFormat 
391f0f96-6d0c-43b9-9efb-c74a2b150a24.pdf150.57 kBAdobe PDFView/Open
Show full item record



CORE Recommender

SCOPUSTM   
Citations

3
checked on May 18, 2024

Page view(s)

96
checked on May 20, 2024

Download(s)

148
checked on May 20, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.