Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.13091/4413
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DC Field | Value | Language |
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dc.contributor.author | Deveci, E. | - |
dc.contributor.author | Tel-Çayan, G. | - |
dc.contributor.author | Çayan, F. | - |
dc.contributor.author | Yılmaz, Altınok, B. | - |
dc.contributor.author | Aktaş, S. | - |
dc.date.accessioned | 2023-08-03T19:03:48Z | - |
dc.date.available | 2023-08-03T19:03:48Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 2193-4126 | - |
dc.identifier.uri | https://doi.org/10.1007/s11694-023-02066-5 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.13091/4413 | - |
dc.description.abstract | This study aimed to investigate HPLC-DAD based chemical compositions, total phenolic compounds, antioxidant, enzyme inhibition and anti-cancer activities of three edible mushrooms: Clavariadelphus truncatus Donk, Craterellus tubaeformis (Fr.) Quél. and Hygrophorus pudorinus (Fr.) Fr. p-Hydroxy benzoic acid was specified as the main compound in C. truncatus methanol extract (67.40 ± 0.18 µg/g), trans-aconitic acid in C. tubaeformis water extract (129.50 ± 0.11 µg/g), fumaric acid in other mushroom extracts (138.80 ± 0.25–203.40 ± 0.36 µg/g). C. truncatus methanol extract (DPPH•: IC50: 133.99 ± 0.30 µg/mL; ABTS•+: IC50: 120.95 ± 0.93 µg/mL; CUPRAC: A0.50: 108.10 ± 0.42 µg/mL; PRAP: A0.50: 116.81 ± 1.18 µg/mL; metal chelating: IC50: 143.18 ± 0.22 µg/mL) was the most active in antioxidant activity with the highest level of total phenolic compounds (29.18 ± 0.70 µg GAEs/mg extract). When C. tubaeformis water extract (42.13 ± 0.51%) was the highest active in AChE inhibition activity, C. tubaeformis hexane extract (29.14 ± 0.04%) was the highest active in BChE inhibition activity at 200 µg/mL. All hexane extracts displayed the high inhibition on α-amylase (47.82 ± 1.16–81.06 ± 0.54% inhibition at 0.50 mg/mL) and α-glucosidase (IC50: 0.11 ± 0.01–0.13 ± 0.02 mg/mL). C. truncatus water (IC50: 36.19 ± 0.95 µg/mL) and C. tubaeformis methanol (IC50: 48.26 ± 0.51 µg/mL) extracts indicated the highest anti-cancer activity on HT-29. Also, C. tubaeformis methanol extract (IC50: 68.93 ± 0.87 µg/mL) was also found to be best anti-cancer active in HeLa. Also, the significant correlation was observed between the chemical compounds and bioactivities. This research affords a scientific basis for the exploration of novel and natural antioxidant, enzyme inhibition and anti-cancer sources with the chemical contents. All studied mushrooms could be used in food, pharmaceutical, and cosmetic applications. © 2023, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. | en_US |
dc.description.sponsorship | Türkiye Bilimsel ve Teknolojik Araştırma Kurumu, TÜBİTAK: TUBITAK-122Z013 | en_US |
dc.description.sponsorship | This study was supported by grants from The Scientific and Technological Research Council of Turkey (TUBITAK-122Z013). | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer | en_US |
dc.relation.ispartof | Journal of Food Measurement and Characterization | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Anti-cancer activity | en_US |
dc.subject | Anti-diabetic activity | en_US |
dc.subject | Anticholinesterase activity | en_US |
dc.subject | Antioxidant activity | en_US |
dc.subject | Edible mushrooms | en_US |
dc.subject | HPLC-DAD characterization | en_US |
dc.subject | Antioxidants | en_US |
dc.subject | Benzoic acid | en_US |
dc.subject | Diseases | en_US |
dc.subject | Extraction | en_US |
dc.subject | Fungi | en_US |
dc.subject | Hexane | en_US |
dc.subject | Methanol | en_US |
dc.subject | Phenols | en_US |
dc.subject | Anti-diabetic activity | en_US |
dc.subject | Anticancer activities | en_US |
dc.subject | Anticholinesterase activities | en_US |
dc.subject | Antidiabetic | en_US |
dc.subject | Antioxidant activities | en_US |
dc.subject | Edible mushroom | en_US |
dc.subject | HPLC-DAD characterization | en_US |
dc.subject | Hplc/dad | en_US |
dc.subject | Inhibition activity | en_US |
dc.subject | Truncatus | en_US |
dc.subject | Enzyme inhibition | en_US |
dc.title | Chemical characterization, in vitro antioxidant, anti-cancer and enzyme inhibition activities of three edible mushroom species | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1007/s11694-023-02066-5 | - |
dc.identifier.scopus | 2-s2.0-85165258334 | en_US |
dc.department | KTÜN | en_US |
dc.identifier.wos | WOS:001035537600005 | en_US |
dc.institutionauthor | … | - |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 56089358000 | - |
dc.authorscopusid | 57743199000 | - |
dc.authorscopusid | 56005323200 | - |
dc.authorscopusid | 58496432200 | - |
dc.authorscopusid | 7007157208 | - |
dc.identifier.scopusquality | Q2 | - |
item.fulltext | No Fulltext | - |
item.openairetype | Article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.languageiso639-1 | en | - |
Appears in Collections: | Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collections |
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