Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.13091/339
Title: A comprehensive study on phenolic compounds and bioactive properties of five mushroom species via chemometric approach
Authors: Çayan, Fatih
Çayan, Gülsen Tel
Deveci, Ebru
Duru, Mehmet Emin
Keywords: Antioxidant Activity
Medicinal-Plants
In-Vitro
Antimicrobial Activity
Free-Radicals
Extracts
Phytochemicals
Disease
Wild
Vivo
Issue Date: 2021
Publisher: WILEY
Abstract: This study was planned to investigate the phenolic compounds, cholinesterase inhibitory, and antioxidant activities of Chondrostereum purpureum (CP), Hymenochaete rubiginosa (HR), Macrolepiota procera (MP), Phaeolus schweinitzii (PS), and Phellinus igniarius (PI) mushroom species. High-performance liquid chromatography (HPLC-DAD) was used for the characterization of the phenolic compounds. The main compound was identified as fumaric acid in C. purpureum (CP), M. procera (MP), and P. igniarius (PI); protocatechuic acid in H. rubiginosa (HR); 6,7-dihydroxy coumarin in P. schweinitzii (PS). P. schweinitzii methanol (PSM) extract had close or higher activity than standards in ABTS(center dot+) (IC50: 2.96 +/- 0.15 mu g/ml), DPPH center dot (80.56 +/- 0.53%), CUPRAC (A(0.50): 5.26 +/- 0.19 mu g/ml), beta-carotene-linoleic acid (IC50: 1.16 +/- 0.14 mu g/ml) assays. In addition, P. schweinitzii methanol (PSM) extract showed potential inhibitory activity against AChE (56.38 +/- 0.09%). The relationship between the phenolic compounds, antioxidant, and cholinesterase inhibitory activity results and the mushroom species were examined using principal component analysis (PCA) and hierarchical cluster analysis (HCA). Practical applications This study revealed that studied mushroom species have significant antioxidant and cholinesterase inhibitory activities and are found to be rich in phenolic compounds. The mushroom species were clustered with their antioxidant and cholinesterase inhibitory activities and phenolic compounds data according to the PCA and HCA analysis. Overall, the results described in this study increase the contribution and emphasis on the potential use of these mushrooms as a source of versatile biological agents.
URI: https://doi.org/10.1111/jfpp.15695
https://hdl.handle.net/20.500.13091/339
ISSN: 0145-8892
1745-4549
Appears in Collections:Mühendislik ve Doğa Bilimleri Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collections

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