Please use this identifier to cite or link to this item:
Title: Full-scale anaerobic digestion of sewage sludges: Fate evaluation of pharmaceuticals and main metabolites
Authors: Dolu, Taylan
Nas, Bilgehan
Keywords: Anaerobic digestion
Pharmaceutically active compounds
Seasonal distribution
Sewage sludge
Soil amendment
Issue Date: 2023
Publisher: Elsevier Ltd
Abstract: The occurrence and behavior of pharmaceuticals especially in sewage sludge have attracted great attention nowadays due to the intensive application of sewage sludge in agriculture in terms of the potential adverse effects of pharmaceuticals. Although anaerobic digestion is a well-developed and widely applied treatment process in terms of stabilization of sewage sludges and removal of organics, the treatment performances of this technology for different pharmaceutical subgroups are still not well known. In this study, the occurrence and seasonal variations of 45 pharmaceutical compounds consisting of 27 parent compounds and 18 main metabolites from 10 different therapeutic groups were investigated both in thickened and digested sludge generated in a large-scale urban wastewater treatment plant (WWTP). In this way, the seasonal removal performances of full-scale anaerobic digesters for parent compounds and metabolites have been determined and compared simultaneously. While the total pharmaceutical concentrations in the thickened sludge varied between 21.1 and 177.6 μg/kg seasonally, it was determined in the range of 21.5 and 88.8 μg/kg in the digested sludge. In the thickened sludge, the predominant group was found as antibiotics (35.9 %), while in the digested sludge, it was determined as anticonvulsants (31.3 %). Besides, seasonal relationships of parent compounds and metabolites both in thickened and digested sludges were evaluated statistically in terms of both occurrence and removal. In general, although the capacities for sorption onto sewage sludges were found as different, removal patterns of both parent compounds and metabolites in anaerobic digesters have been determined as quite similar. The removal performance of the anaerobic digesters showed great differences based on the investigated pharmaceutical subgroups. Although varies seasonally, while antibiotic (up to 82.9 %), NSAID (up to 70.9 %), and nerve stimulant (up to 89.6 %) groups tended to be treated in anaerobic digesters, negative removal efficiencies were determined for anticonvulsant (up to −242.9 %), steroid hormone (up to −155.3 %) and antidepressant (up to −5010 %) groups. While the total pharmaceutical treatment performances of anaerobic sludge digesters varied between −78 % (in summer) and 65 % (in winter) seasonally, it has been determined as 28.5 % annually. Therefore, it has been determined in this study that the pharmaceutical treatment performance of full-scale anaerobic digesters is not effective enough. © 2022 Elsevier Ltd
ISSN: 2214-7144
Appears in Collections:Mühendislik ve Doğa Bilimleri Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collections

Files in This Item:
File SizeFormat 
  Until 2030-01-01
2.6 MBAdobe PDFView/Open    Request a copy
Show full item record

CORE Recommender


checked on Oct 27, 2023

Page view(s)

checked on Dec 4, 2023


checked on Dec 4, 2023

Google ScholarTM



Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.