Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.13091/1394
Title: Toxicological evaluation of carbamazepine active pharmaceutical ingredient with Lepidium sativum, Daphnia magna and Vibrio fischeri toxicity test methods
Authors: Tongur, Süheyla
Yıldız, Sevil
Fakülteler, Mühendislik ve Doğa Bilimleri Fakültesi, Çevre Mühendisliği Bölümü
#PLACEHOLDER_PARENT_METADATA_VALUE#
Keywords: Acute Toxicity
Carbamazepine
Pharmaceutical
Toxicity Tests
Toxic Unit
Waste-Water
Mass-Spectrometry
Hormones
Risks
Issue Date: 2020
Publisher: DESALINATION PUBL
Abstract: Pharmaceuticals have been found extensively within an aquatic environment. Carbamazepine was one of them that was found at the highest frequency and amounts. The persistence of these micropollutants in the environment is of concern because of a combination of characteristics, which includes the toxicity of humans and animal health. In this study, acute toxicity from carbamazepine, which is regularly used in anti-epileptic pharmaceuticals, was investigated using Lepidium sativum (L. sativum), Daphnia magna (D. magna), and Vibrio fischeri (V. fischeri) toxicity test methods. These different toxicity test methods were used and their sensitivities were compared. The results obtained from all experiments were evaluated according to the applied method. Accordingly, electrical conductivity (EC50) (the 50% effect concentration) values ranged from 9.53 to 94.39 mg/L. The test results were expressed as toxic unit (TU) which were calculated as 1.05 for L. sativum, 10.49 for D. magna, and 2.7 for V. fischeri. According to the TU values, sensitivities were D. magna > V. fischeri > L. sativum, respectively. The most sensitive values were obtained from D. magna toxicity test method.
Description: 1st International Conference on Environment, Technology and Management (ICETEM) -- JUN 27-29, 2019 -- Nigde, TURKEY
URI: https://doi.org/10.5004/dwt.2020.25969
https://hdl.handle.net/20.500.13091/1394
ISSN: 1944-3994
1944-3986
Appears in Collections:Mühendislik ve Doğa Bilimleri Fakültesi Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collections

Files in This Item:
File SizeFormat 
201_2020_438_DESWATER.manuscript1.pressed (1).pdf414.39 kBAdobe PDFView/Open
Show full item record



CORE Recommender

SCOPUSTM   
Citations

2
checked on Mar 2, 2024

WEB OF SCIENCETM
Citations

5
checked on Mar 2, 2024

Page view(s)

202
checked on Mar 4, 2024

Download(s)

62
checked on Mar 4, 2024

Google ScholarTM

Check




Altmetric


Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.