Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.13091/1394
Title: | Toxicological evaluation of carbamazepine active pharmaceutical ingredient with Lepidium sativum, Daphnia magna and Vibrio fischeri toxicity test methods | Authors: | Tongur, Süheyla Yıldız, Sevil |
Keywords: | Acute Toxicity Carbamazepine Pharmaceutical Toxicity Tests Toxic Unit Waste-Water Mass-Spectrometry Hormones Risks |
Publisher: | DESALINATION PUBL | Abstract: | Pharmaceuticals have been found extensively within an aquatic environment. Carbamazepine was one of them that was found at the highest frequency and amounts. The persistence of these micropollutants in the environment is of concern because of a combination of characteristics, which includes the toxicity of humans and animal health. In this study, acute toxicity from carbamazepine, which is regularly used in anti-epileptic pharmaceuticals, was investigated using Lepidium sativum (L. sativum), Daphnia magna (D. magna), and Vibrio fischeri (V. fischeri) toxicity test methods. These different toxicity test methods were used and their sensitivities were compared. The results obtained from all experiments were evaluated according to the applied method. Accordingly, electrical conductivity (EC50) (the 50% effect concentration) values ranged from 9.53 to 94.39 mg/L. The test results were expressed as toxic unit (TU) which were calculated as 1.05 for L. sativum, 10.49 for D. magna, and 2.7 for V. fischeri. According to the TU values, sensitivities were D. magna > V. fischeri > L. sativum, respectively. The most sensitive values were obtained from D. magna toxicity test method. | Description: | 1st International Conference on Environment, Technology and Management (ICETEM) -- JUN 27-29, 2019 -- Nigde, TURKEY | URI: | https://doi.org/10.5004/dwt.2020.25969 https://hdl.handle.net/20.500.13091/1394 |
ISSN: | 1944-3994 1944-3986 |
Appears in Collections: | Mühendislik ve Doğa Bilimleri Fakültesi Koleksiyonu Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collections |
Files in This Item:
File | Size | Format | |
---|---|---|---|
201_2020_438_DESWATER.manuscript1.pressed (1).pdf | 414.39 kB | Adobe PDF | View/Open |
CORE Recommender
SCOPUSTM
Citations
2
checked on Oct 12, 2024
WEB OF SCIENCETM
Citations
6
checked on Oct 12, 2024
Page view(s)
444
checked on Oct 14, 2024
Download(s)
232
checked on Oct 14, 2024
Google ScholarTM
Check
Altmetric
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.