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https://hdl.handle.net/20.500.13091/1363
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Çayan, Gülsen Tel | - |
dc.contributor.author | Muhammad, Akhtar | - |
dc.contributor.author | Deveci, Ebru | - |
dc.contributor.author | Duru, Mehmet Emin | - |
dc.contributor.author | Öztürk, Mehmet | - |
dc.date.accessioned | 2021-12-13T10:38:47Z | - |
dc.date.available | 2021-12-13T10:38:47Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 0141-8130 | - |
dc.identifier.issn | 1879-0003 | - |
dc.identifier.uri | https://doi.org/10.1016/j.ijbiomac.2020.10.040 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.13091/1363 | - |
dc.description.abstract | Polysaccharides are essential compounds that contribute to the biological activities of mushrooms. Two new galactomannans (Galactomannan I and II) were isolated from R. luteolus and G. adspersum. Their structures were characterized using FT-IR, 1D, and 2D-NMR techniques. Both isolated galactomannans I and II mainly include D-mannose and D-galactose in the molar percentages of 0.81:1.0 and 1:1.4, respectively. The GPC calculation demonstrated that the molecular weights are about 5240 and 5090 Da, respectively. Their structures comprise of beta-(1,4)-mannose (Man) backbone units with alpha-(1,6)-galactose (Gal) single unit as a side group. The anticholinesterase activity of galactomannans was tested against acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), spectrophotometrically. Antioxidant activity was also measured by six assays (ABTS(center dot+), DPPH center dot, O-2(center dot-), beta-carotene-linoleic acid, metal chelating, and CUPRAC assays). Galactomannan II indicated close inhibitory activity to galantamine against AChE (61.04 +/- 0.45%) and BChE (59.70 +/- 1.15%) at 50 mu g/mL concentration. Nevertheless, both galactomannans showed low antioxidant activity in all tests. This study reveals that mainly, Galactomannan II could be used as a new natural promising anticholinesterase agent. (C) 2020 Elsevier B.V. All rights reserved. | en_US |
dc.description.sponsorship | Scientific and Technological Research Council of TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TUBITAK-TBAG109T933] | en_US |
dc.description.sponsorship | This study was supported by the Scientific and Technological Research Council of Turkey through the project (TUBITAK-TBAG109T933). The authors would like to thank Dr. Aziz Turkoglu for the identification of the mushroom samples. | en_US |
dc.language.iso | en | en_US |
dc.publisher | ELSEVIER | en_US |
dc.relation.ispartof | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Rhizopogon Luteolus | en_US |
dc.subject | Ganoderma Adspersum | en_US |
dc.subject | Galactomannan | en_US |
dc.subject | Characterization | en_US |
dc.subject | Antioxidant Activity | en_US |
dc.subject | Anticholinesterase Activity | en_US |
dc.subject | Water-Soluble Polysaccharides | en_US |
dc.subject | Anticholinesterase Activities | en_US |
dc.subject | 3-O-Methylated Mannogalactan | en_US |
dc.subject | Antioxidant | en_US |
dc.subject | Antitumor | en_US |
dc.subject | Florida | en_US |
dc.subject | Seeds | en_US |
dc.subject | Purification | en_US |
dc.subject | Heteroglycan | en_US |
dc.subject | Elucidation | en_US |
dc.title | Isolation, structural characterization, and biological activities of galactomannans from Rhizopogon luteolus and Ganoderma adspersum mushrooms | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1016/j.ijbiomac.2020.10.040 | - |
dc.identifier.pmid | PubMed: 33065160 | en_US |
dc.identifier.scopus | 2-s2.0-85094586314 | en_US |
dc.department | Fakülteler, Mühendislik ve Doğa Bilimleri Fakültesi, Kimya Mühendisliği Bölümü | en_US |
dc.authorid | Ozturk, Mehmet/0000-0001-8932-4535 | - |
dc.authorwosid | DURU, Mehmet Emin/ABA-2426-2021 | - |
dc.authorwosid | Ozturk, Mehmet/W-4649-2017 | - |
dc.identifier.volume | 165 | en_US |
dc.identifier.startpage | 2395 | en_US |
dc.identifier.endpage | 2403 | en_US |
dc.identifier.wos | WOS:000600773500073 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 57194732739 | - |
dc.authorscopusid | 54796831700 | - |
dc.authorscopusid | 56089358000 | - |
dc.authorscopusid | 12789661400 | - |
dc.authorscopusid | 7102665882 | - |
dc.identifier.scopusquality | Q1 | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | embargo_20300101 | - |
item.languageiso639-1 | en | - |
item.openairetype | Article | - |
item.fulltext | With Fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
crisitem.author.dept | 07. 04. Department of Chemistry and Chemical Processing Technologies | - |
Appears in Collections: | Mühendislik ve Doğa Bilimleri Fakültesi Koleksiyonu PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collections Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collections |
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