Please use this identifier to cite or link to this item: https://hdl.handle.net/20.500.13091/1298
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dc.contributor.authorŞimşir, Evin Ayşegül-
dc.contributor.authorErdemir, Serkan-
dc.contributor.authorTabakcı, Mustafa-
dc.contributor.authorTabakcı, Begüm-
dc.date.accessioned2021-12-13T10:38:41Z-
dc.date.available2021-12-13T10:38:41Z-
dc.date.issued2021-
dc.identifier.issn0003-2670-
dc.identifier.issn1873-4324-
dc.identifier.urihttps://doi.org/10.1016/j.aca.2021.338494-
dc.identifier.urihttps://hdl.handle.net/20.500.13091/1298-
dc.description.abstractIt is crucial to determine and control the metronidazole (MET) ingredient in food and pharmaceuticals for human health and food safety. Even though many sensors have been previously reported to detect MET, there is still a need for a highly selective and sensitive, easy, fast, cost-effective sensor in this area. Herein, we report a fluorescent calix[4]arene derivative (PIMC) for highly selective and sensitive and facile and rapid MET detection based on fluorescence (FL) quenching. The highest FL quenching occurs when PIMC is exposed to MET solution at 400 nm (lambda(ex) = 340). Owing to the quenching efficacy of MET linearly up to 5.5 x 10(4) nM was obtained a detection limit of 2.44 nM. Besides, interferences of other pharmaceuticals and ions on probe performance were investigated. The FL probe was successful in MET detection without the assistance of any separation techniques in a pharmaceutical sample (tablet) with an acceptable recovery of 101.3%. The applicability of the current probe as a paper-based sensor to MET detection has been successfully tested. As a result, the proposed probe presents a fast and suitable strategy to sensitive and selective detect MET and proves a good potential for practical applications, especially pharmaceutical preparations. (C) 2021 Elsevier B.V. All rights reserved.en_US
dc.language.isoenen_US
dc.publisherELSEVIERen_US
dc.relation.ispartofANALYTICA CHIMICA ACTAen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMetronidazoleen_US
dc.subjectCalixareneen_US
dc.subjectFluorescenceen_US
dc.subjectPharmaceuticalen_US
dc.subjectOptical Sensoren_US
dc.subjectQuenchingen_US
dc.subjectMolecularly Imprinted Polymersen_US
dc.subjectElectrochemical Sensoren_US
dc.subjectCarbonen_US
dc.subjectFabricationen_US
dc.subjectVoltammetryen_US
dc.subjectSwitchen_US
dc.titleNano-scale selective and sensitive optical sensor for metronidazole based on fluorescence quenching: 1H-Phenanthro[9,10-d]imidazolyl-calix[4]arene fluorescent probeen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.aca.2021.338494-
dc.identifier.pmidPubMed: 33926701en_US
dc.identifier.scopus2-s2.0-85104074013en_US
dc.departmentFakülteler, Mühendislik ve Doğa Bilimleri Fakültesi, Kimya Mühendisliği Bölümüen_US
dc.authoridTabakci, Begum/0000-0003-4735-2882-
dc.identifier.volume1162en_US
dc.identifier.wosWOS:000641346100001en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid57222812815-
dc.authorscopusid13610351500-
dc.authorscopusid6506600394-
dc.authorscopusid8587997700-
dc.identifier.scopusqualityQ1-
item.openairetypeArticle-
item.languageiso639-1en-
item.cerifentitytypePublications-
item.grantfulltextembargo_20300101-
item.fulltextWith Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
crisitem.author.dept02.01. Department of Chemical Engineering-
Appears in Collections:Mühendislik ve Doğa Bilimleri Fakültesi Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collections
Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections
WoS İndeksli Yayınlar Koleksiyonu / WoS Indexed Publications Collections
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