Profile URL: https://hdl.handle.net/20.500.13091/11909
Email Address:edeveci@ktun.edu.tr
Main Affiliation:07. 04. Department of Chemistry and Chemical Processing Technologies
Status: Current Staff
ORCID:
0000-0002-2597-9898
0000-0002-2597-9898Scopus ID:
56089358000
56089358000YÖK Akademik: D821E2C50EC89B1C
Google Scholar:
aF5BsbEAAAAJ
aF5BsbEAAAAJWeb of Science ID:
ABF-6243-2021
ABF-6243-2021Name Variants:
Deveci, E.
31 results
Scholarly Output Search Results
Now showing 1 - 10 of 31
Article Citation - Scopus: 3Anti-Colorectal Cancer Effects of Medicinal Plants: Euphorbia Helioscopia, Ferula Elaeochytris, and Sideritis Albiflora(2020-06-30) Deveci, Ebru; Çayan, Gülsen Tel; Karakurt, Serdar; Duru, Mehmet Emin; Tel-çayan, GulsenPhytochemicals, extracts, and mixtures obtained from plants have been offered as an option for cancer treatment and prevention for modern drug discovery in recent years. For this purpose, in this study, anti-colorectal cancer effects of the hexane, acetone, methanol, and water extracts obtained by sequential extraction from Euphorbia helioscopia L., Ferula elaeochytris Korovin, and Sideritis albiflora Hub.-Mor. on DLD-1 cell line were investigated in vitro by using Alamar blue assay. Dosedependent inhibition was detected in the viability of DLD-1 cell line. In all three plants species, E. helioscopia (IC50: 140.83±0.31 µg/mL), F. elaeochytris (IC50: 67.93±0.12 µg/mL), and S. albiflora (IC50: 85.12±0.10 µg/mL) methanol extracts showed higher anti-colorectal effects on DLD-1 cell line compared to other extracts tested for the same species. In addition, the IC50 value of doxorubicin used as a standard was found as 6.10±0.55 µg/mL. With the results obtained, as the first report highlighting in vitro anti-colorectal cancer effects of the studied plant species on DLD-1 cell line, promising marks were obtained from the analysis of the extracts as anti-cancer sources for plant-derived drug applications.Article Citation - WoS: 13Citation - Scopus: 15Chemometric Approaches for the Characterization of the Fatty Acid Composition of Seventeen Mushroom Species(TAYLOR & FRANCIS INC, 2020-05-02) Çayan, Fatih; Deveci, Ebru; Çayan, Gülsen Tel; Duru, Mehmet Emin; Tel-Cayan, GulsenMushrooms have been used since ancient times because of their nutritional, medicinal and economic potential. In this study, fatty acid compositions of seventeen mushroom species, naturally growing in Turkey, were determined by using gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Totally, twenty-four fatty acids were identified in mushroom species. Generally, oleic (6.76-59.25%), linoleic (6.45-61.63%), palmitic (3.57-28.09%) and stearic (0.90-19.77%) acids were identified as the main fatty acids in all studied mushroom species. Principal component analyses (PCA) and hierarchical clustering analyses (HCA) were applied to analyze the chemometry of twenty-four fatty acids of the seventeen mushroom species by using Minitab 16.0 software. The main fatty acid compounds found in the mushrooms and their concentrations have been effective in distinguishing mushroom species from each other. As a result of PCA and HCA analysis, it was determined that Daedalea quercina (DQ) was distinctly separated from other mushroom species in terms of fatty acid composition. This study reveals that the chemometric analysis by PCA and HCA techniques could be used for the classification of the mushroom species according to their fatty acid compositions.Article Cytotoxic Activities of Methanol Extract and Compounds of Porodaedalea Pini Against Colorectal Cancer(2021-03-08) Karakurt, Serdar; Deveci, Ebru; Tel-çayan, Gulsen; Duru, Mehmet EminPorodaedalea pini is a medicinally important mushroom withantioxidant, cytotoxic, immunostimulating, antitumor, antiviral andimmunomodulating activities. Therefore, in this study, P. pini methanol extractand isolated compounds from the methanol extract were tested for cytotoxicactivities against DLD-1 (colorectal cancer) and CCD-18Co (human colonfibroblast cell line) by using Alamar Blue assay. Cytotoxic activity on DLD-1was decreased in the order of P. pini methanol extract> 4-(3,4-dihydroxyphenyl)but-3-en-2-one (3)> pinoresinol (2)> ergosta-7,24(28)-dien3β-ol (1). P. pini methanol extract was determined to have the best cytotoxicactivity with the lowest IC50 value on DLD-1 (IC50: 25.33±0.29 µg/mL) and thehighest IC50 value on CCD-18Co (434.30±1.45 µg/mL). Within the scope of thefindings, it is thought that P. pini mushroom can be used as a new and naturalagent in the treatment of colorectal cancer.Article Citation - WoS: 12Citation - Scopus: 14Chemometrics Evaluation of Phytochemicals and Antioxidant Activities of the Extracts of Chaerophyllum Bulbosum Roots and Aerial Parts(TAYLOR & FRANCIS INC, 2021-06-21) Çayan, Gülsen Tel; Deveci, Ebru; Çayan, Fatih; Molo, Zeynep; Duru, Mehmet Emin; Yeşil, Yeter; Tel-Cayan, GulsenThe objective of this study was provide the first report to assess the high-performance liquid chromatography-diode array detection (HPLC-DAD) identification of phytochemicals, the spectrophotometric determination of total phenolics and flavonoids, and antioxidant activities of the root and aerial extracts of Chaerophyllum bulbosum. HPLC-DAD identified the main phytochemical to be rosmarinic acid in the roots in the acetone (CBRA) (13.98 +/- 0.12 mg/g) and the aerial water (CBAW) extract; myricetin (8.30 +/- 0.22 mg/g) in the root methanol extract (CBRM); trans-aconitic acid (6.46 +/- 0.49 mg/g) in the root water extract (CBRW) and fumaric acid in the aerial methanol (CBAM) (17.43 +/- 0.87 mg/g) and water CBAW (18.96 +/- 0.81 mg/g) extracts. The concentrations of total phenolics and flavonoids were 2.00 +/- 0.14-17.79 +/- 0.99 mu g PEs/mg extract and 2.90 +/- 0.00-27.64 +/- 0.37 mu g QEs/mg extract, respectively. The highest antioxidant activity was found in the root acetone extract (CBRA) using the beta-carotene-linoleic (IC50: 172.31 +/- 0.16 mu g/mL) and CUPRAC (A(0.50): 126.00 +/- 0.24 mu g/mL) assays and in the root water extract (CBRW) for DPPH center dot (IC50: 59.51 +/- 0.21 mu g/mL) and metal chelating (IC50: 65.91 +/- 0.36 mu g/mL) assays in the aerial water extract (CBAW) using the ABTS(center dot+) (IC50: 59.51 +/- 0.21 mu g/mL) assay. The relationship between the phytochemicals and antioxidant activities of the extracts was chemometrically determined by principal component analysis (PCA) and hierarchical cluster analysis (HCA).Article Isolation and Characterization of Chemical Constituents From Chaerophyllum Bulbosum Roots and Their Enzyme Inhibitory and Antioxidant Effects(Walter De Gruyter Gmbh, 2021-07-06) Tel-Çayan, Gülşen; Deveci, Ebru; Molo, Zeynep; Duru, Mehmet Emin; Öztürk, MehmetIsolation and bioactive effects of the roots of Chaerophyllum bulbosum L. were firstly investigated herein. Enzyme (acetylcholinesterase, butyrylcholinesterase, urease, alpha-amylase, alpha-glucosidase, and tyrosinase) inhibitory effects of C. bulbosum root extracts were tested. Three known compounds, n-heptadecanyl eicosanoate (1), stigmasterol (2), and beta-sitosterol-3-O-beta-d-glucopyranoside (3) were isolated from C. bulbosum. Antioxidant and enzyme inhibitory effects of isolated compounds were investigated. The hexane extract (IC50: 349.58 +/- 0.06 mu g/mL) displayed a higher alpha-glucosidase inhibitory effect than the standard (IC50: 378.66 +/- 0.14 mu g/mL). The best inhibitory effect was found in compound 2 on AChE (46.40 +/- 0.31%), BChE (56.41 +/- 0.54%), and urease (92.47 +/- 0.11%); compound 1 on alpha-amylase (22.27 +/- 0.61%); and compound 3 on alpha-glucosidase (12.43 +/- 0.25%) and tyrosinase (19.00 +/- 0.16%). All isolated compounds showed moderate antioxidant effects in all assays. This study contributes to the therapeutic uses of Chaerophyllum roots and emphasizes the value of C. bulbosum species for the development of novel therapeutic agents.Article Citation - WoS: 12Citation - Scopus: 16Characterization of Polysaccharide Extracts of Four Edible Mushrooms and Determination of in Vitro Antioxidant, Enzyme Inhibition and Anticancer Activities(Amer Chemical Soc, 2024-06-06) Deveci, Ebru; Tel-Cayan, Gülsen; Cayan, Fatih; Altinok, Bahar Yilmaz; Aktaş, Sinan; Yılmaz Altınok, BaharMushroom polysaccharides are important bioactive compounds derived from mushrooms with various beneficial properties. In this study, the chemical characterization and bioactivities of polysaccharide extracts from four different edible mushrooms, Clavariadelphus truncatus Donk, Craterellus tubaeformis (Fr.) Quel., Hygrophorus pudorinus (Fr.) Fr., and Macrolepiota procera (Scop.) Singer were studied. Glucose (13.24-56.02%), galactose (14.18-64.05%), mannose (2.18-18.13%), fucose (1.21-5.78%), and arabinose (0.04-5.43%) were identified in all polysaccharide extracts by GC-MS (gas chromatography-mass spectrometry). FT-IR (Fourier transform infrared spectroscopy) confirmed the presence of characteristic carbohydrate patterns. H-1 NMR suggested that all polysaccharide extracts had alpha- and beta-d-mannopyranose, d-glucopyranose, d-galactopyranose, alpha-l-arabinofuranose, and alpha-l-fucopyranose residues. Approximate molecular weights of polysaccharide extracts were determined by HPLC (high-performance liquid chromatography). The best antioxidant activity was found in M. procera polysaccharide extract in DPPH center dot (1,1-diphenyl-2-picrylhydrazyl) scavenging (39.03% at 800 mu g/mL), CUPRAC (cupric reducing antioxidant capacity) (A(0.50): 387.50 mu g/mL), and PRAP (phosphomolybdenum reducing antioxidant power) (A(0.50): 384.08 mu g/mL) assays. C. truncatus polysaccharide extract showed the highest antioxidant activity in ABTS(center dot+) scavenging (IC50: 734.09 mu g/mL), beta-carotene-linoleic acid (IC50: 472.16 mu g/mL), and iron chelating (IC50: 180.35 mu g/mL) assays. Significant anticancer activity was found in C. truncatus polysaccharide extract on HT-29 (IC50: 46.49 mu g/mL) and HepG2 (IC50: 48.50 mu g/mL) cell lines and H. pudorinus polysaccharide extract on the HeLa cell line (IC50: 51.64 mu g/mL). Also, H. pudorinus polysaccharide extract possessed prominent AChE (acetylcholinesterase) inhibition activity (49.14% at 200 mu g/mL).Article Assessment of Cytotoxic Effect of Porodaedalea Pini Mushroom on Prostate Cancer(2022) Deveci, Ebru; Duru, Mehmet Emin; Çayan, Gülsen Tel; Tel-çayan, GulsenPhellinus species are in the classification of valuable mushrooms among medicinal mushrooms and have been the source of traditional medicine for centuries. In this study, the hexane (PPH), methanol (PPM) and water (PPW) extracts, fractions and isolated compounds from Porodaedalea pini (Çamkavı mantarı) were screened for their cytotoxic effects on PC3 (prostate cancer) and 3T3 (murine fibroblast) cell lines by MTT assay. PPH was found to have moderate cytotoxicity on PC3 cell with the IC50 values of 33.84±0.01 µg/mL. The fatty acid profile of PPH was identified by GC-FID (gas chromatography-flame ionization dedector) and GC-MS (gas chromatography-mass spectrometry) and the main fatty acids were recorded as palmitic (41.40±0.03%), linoleic (21.53±0.01%), oleic (12.06±0.01%), and stearic (8.20±0.01%) acids. PPM and PPW were fractioned by using liquid-liquid extractions. Among all fractions, the 2-butanol fraction of the methanol extract (PPM-B) indicated the best cytotoxicity on PC3 and 3T3 cell lines. Also, among the isolated compounds (dioctyl phthalate (1), ergosterol peroxide (2) and pinoresinol (3)) from PPM, ergosterol peroxide (2) was found as moderate cytotoxic on PC3 with the IC50 value of 95.47±1.01 µg/mL. This study, in which the effect of P. pini on PC3 cell was examined for the first time, proved its medicinal importance by revealing the cytotoxic properties of the species.Article Citation - WoS: 83Citation - Scopus: 98Identification and Quantification of Phenolic Acid Compounds of Twenty-Six Mushrooms by Hplc-Dad(SPRINGER, 2020-02-17) Çayan, Fatih; Deveci, Ebru; Çayan, Gülsen Tel; Duru, Mehmet Emin; Tel-Cayan, GulsenPhenolic acids are found in different foods in the human diet, for example mushrooms. Determination of phenolic acids is important because of their relationship to their role in disease prevention due to their bioactive properties. In this study, the phenolic acid profile of 26 mushroom species was analyzed by using high-performance liquid chromatography method coupled with photodiode array detector (HPLC-DAD) and 16 phenolic acid compounds were identified. The chromatographic separation was performed using Intertsil ODS-3 reverse phase C-18 column (5 mu m, 250 mm x 4.6 mm i.d), gradient solvent system with 1.5 mL/min flow rate and detected at 280 nm. The coefficient of determination (R-2) was in the range of 0.9965-0.9999. Limit of detection and quantification ranged from 0.001-0.970 to 0.001-2.940 mu g/L, respectively. The phenolic compounds were characterized according to their retention times and UV data were compared with commercial standards. S. granulatus (71.79 mu g/g) and L. nuda (68.38 mu g/g) revealed the highest concentration of total phenolic compounds among the studied mushrooms. Gallic acid was found as the major phenolic compound in R. aurora (2.96 +/- 0.56 mu g/g) while 6,7-dihydroxy coumarin was identified as major phenolic compounds in A. tabescens (2.07 +/- 0.25 mu g/g) and L. leucothites (9.02 +/- 0.87 mu g/g). Fumaric acid was found as the most abundant compounds in 16 out of 26 mushrooms. Catechin hydrate was identified as major phenolic compounds in the rest of mushrooms. This method provided a beneficial standardization procedure of phenolic acid compounds in mushroom samples.Article Citation - Scopus: 1Characterization of Chemical Compounds of Fractions From Four Different Bee Pollens With Chemometric Classification(Springer Science and Business Media Deutschland GmbH, 2025-01-31) Tel-Çayan, G.; Çayan, F.; Deveci, E.; Karataş, Ş.; Duru, M.E.Bee pollen continues to increase its popularity as a ‘complete food’ among natural resources with its high health value and therapeutic chemical compounds. This study focused on HPLC-DAD (high-performance liquid chromatography-diode array detection) based on the identification of chemical compounds of Cistus creticus, Helianthus annuus, Papaver somniferum and Salix sp. bee pollens. Also, water extracts and the fractions (hexane, dichloromethane, ethyl acetate, butanol, water) obtained from the methanol extracts of all bee pollens were investigated for chemical compounds. A total of 29 chemical compounds were screened and kaempferol was detected in all studied bee pollen samples at concentration of 0.4 and 331.6 µg/g. Luteolin (68.7–694.8 µg/g), trans-aconitic acid (12.2–479.1 µg/g), myricetin (160.4–1534.2 µg/g), quercetin (162.1–608.1 µg/g), rosmarinic acid (273.8–435.6 µg/g), rutin (3.6–202.8 µg/g), and trans-cinnamic acid (5.1–1854.6 µg/g) were found as the most abundant chemical compounds. Additionally, nonpolar and polar fractions of the bee pollens were chemometrically clustered for similarities and differences of chemical compounds via principal component analysis (PCA) and hierarchical cluster analysis (HCA). In nonpolar fractions, C. creticus, H. annuus, P. somniferum, and Salix sp. ethyl acetate fractions (CEA, HEA, PEA, SEA) were separated from other fractions, while in polar fractions, C. creticus, H. annuus, P. somniferum, and Salix sp. butanol fractions (CB, HB, PB, SB) were separated from other fractions. This study provides additional data on the characterization of valuable chemical compounds in bee pollens and constitutes a beginning in the chemometric classification of chemical compounds. © The Author(s) 2025.Article Citation - WoS: 9Citation - Scopus: 10The Effects of the Use of Vegetable Oil Based as Engine Lubrication Oil on Engine Performance and Emissions in Diesel Engines(TAYLOR & FRANCIS INC, 2019-10-11) Öğüt, H.; Oğuz, H.; Aydın, F.; Ciniviz, M.; Deveci, EbruThe boron occupies an important place on contributions and its usage is getting widespread. Although the use of boron-added mineral oils serves to reduce friction, environmental risks can not be totally removed. It is necessary to improve the properties of biological oils used for additives so that they can compete with mineral oils technically. In the study, the use of liquid boron as an additive for engine lubrication oil together with vegetable oil was investigated experimentally in two diesel engines. Experiments were first carried out using mineral lubrication oil in the engine, and then the experiments were repeated using mineral base oil with additives in the second engine with the same technical characteristics as the first engine. Basically, the study was performed in the fields of engine performance (torque, power, consumption per hour, specific fuel consumption) and exhaust emissions (CO, CO2, HC, O-2, SO2, NOx). As a result, it was concluded that the engine, in which boron and mineral oil with wild mustard oil were used, provided more significant fuel saving than in the engine with additive-free mineral oil, and no significant change was seen in the engine performance, also they showed similarities in terms of exhaust emissions.
Research Topics
Domains
Health SciencesLife Sciences
Fields
MedicinePharmacology, Toxicology and PharmaceuticsAgricultural and Biological Sciences
Subfields
PharmacologyBiochemistryFood SciencePlant Science
Specific Research Areas
Fungal Biology and Applications
Phytochemicals and Antioxidant Activities
Phytochemistry and Bioactivity Studies
Essential Oils and Antimicrobial Activity
Phytochemistry and Biological Activities
Sustainable Development Goals
3GOOD HEALTH AND WELL-BEING
13
Research Products
9INDUSTRY, INNOVATION AND INFRASTRUCTURE
2
Research Products
13CLIMATE ACTION
1
Research Products
Documents
41
Citations
716
h-index
16
Documents
0
Citations
0
Publication Collaboration
| Affiliation Name | Count |
|---|---|
| Muğla University | 40 |
| Konya Technical University | 28 |
| Karamanoğlu Mehmetbey University | 7 |
| Selçuk University | 6 |
| Hasan Kalyoncu University | 3 |
1 / 3
Data obtained from OpenAlex
| Journal | Count |
|---|---|
| Commagene Journal of Biology | 4 |
| International Journal of Secondary Metabolite | 2 |
| Journal of Food Measurement and Characterization | 2 |
| JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION | 2 |
| European Journal of Biology | 2 |
Current Page: 1 / 5
Scholarly Output
31
Articles
31
Views / Downloads
92/76
Supervised MSc Theses
0
Supervised PhD Theses
0
WoS Citation Count
285
Scopus Citation Count
385
Patents
0
Projects
0
WoS Citations per Publication
9.19
Scopus Citations per Publication
12.42
Open Access Source
13
Supervised Theses
0
Scopus Quartile Distribution
Competency Cloud
