PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collections

Permanent URI for this collectionhttps://hdl.handle.net/20.500.13091/5

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Automatic Phase Reversal Detection in Routine Eeg
(CHURCHILL LIVINGSTONE, 2020) Yıldırım, Sema; Koçer, Hasan Erdinç; Ekmekçi, Ahmet Hakan
Electroencephalograph (EEG), a valuable tool in the clinical evaluation, is readily available, safe and provides information about brain function. EEG interpretation is important for the diagnosis of neurological disorders. The long-term EEG data may be required to document and study neurosciences that include many epileptic activities and phase reversal (PR) etc. However, analyze of the long-term EEG done by an expert neurologist is much time consuming and quite difficult. Therefore, an automatic PR determination method for analyzing of long-term EEG is described in this study. The presented technique was applied to the pathological EEG recordings that were obtained from two different datasets gathered as a retrospective in Selcuk University Hospital (SUH) and Boston Children's Hospital (BCH). With this method, PR in the dataset was determined and then compared with the ones detected by the specialist doctor. Two tests were carried out in the SUH dataset and the classification success of the method was 83.22% for test 1 and 85.19% for test 2. On the other hand, three tests were carried out for two different position values for BCH dataset. The highest classification success of the six tests was 75% for test 5, while the lowest classification success appeared as 58.33% for test 6. As a result, the overall success in the detection of PR with the conducted method is 84.20% for SUH and 66.7% for BCH. According to these results, the determination of PR that is known to be indicative of neurological disorders and presenting them to expert information will accelerate the interpretation of long-term EEG recordings.
Citation - WoS: 8
Citation - Scopus: 9
An Experimental Performance Comparison of Newtonian and Non-Newtonian Fluids on a Centrifugal Blood Pump
(Sage Publications Ltd, 2022) Önder, Ahmet; Yapıcı, Rafet; İncebay, Ömer
The use of substitute fluid with similar rheological properties instead of blood is important due to ethical concerns and high blood volume consumption in pump performance test before clinical applications. The performance of a centrifugal blood pump with hydrodynamic journal bearing is experimentally tested using Newtonian 40% aqueous glycerin solution (GS) and non-Newtonian aqueous xanthan gum solution of 600 ppm (XGS) as working fluids. Experiments are performed at four different rotational speeds which are 2700, 3000, 3300, and 3600 rpm; experiments using GS reach between 8.5% and 37.2% higher head curve than experiments using the XGS for every rotational speed. It was observed that as the rotational speed and flow rate increase, the head curve difference between GS and XGS decreases. This result can be attributed to the friction reduction effect when using XGS in experiments at high rotation speed and high flow rate. Moreover, due to different fluid viscosities, differences in hydraulic efficiency were observed for both fluids. This study reveals that the use of Newtonian fluids as working fluids is not sufficient to determine the actual performance of a blood pump, and the performance effects of non-Newtonian fluids are remarkably important in pump performance optimizations.
Citation - WoS: 1
Citation - Scopus: 1
Paramagnetic Characterization of Fossil Mollusc Shells at Eastern Part of the Old Konya Lake: Its Importance for Epr Dating
(Oxford Univ Press, 2023) Ekici, Gamze; Sayın, Ülkü; Işık, Mesut; Kapan, Sevinc; Demir, Ahmet; Aydın Karaaslan, Hülya; Delikan, Arif
Fossil mollusc shells are used for dating geological materials because they are well preserved throughout geological time. In this study, the radicals in the structure of fossil mollusc shells (Dreissena iconica, Valvata piscinalis, Bithynia tentaculate, Unio pictorum) collected from the Eastern Part of Old Konya Lake in Turkiye were investigated by EPR technique. For all fossil shells, microwave and temperature dependence of the signals were examined, and the signals suitable for dating are discussed. Characteristic features of intrinsic and impurity-related radicals were identified and the importance of paleontological evaluation of molluscs to get a reliable equivalent dose in EPR dating studies was emphasised.
Citation - WoS: 3
Citation - Scopus: 5
Study on Phenolic and Organic Acid Compositions and Antioxidant and Enzyme Inhibition Activities of Agaricomycetes Mushroom Species From Turkey
(Begell House Inc., 2023) Tel-çayan, G.; Deveci, E.; Çayan, F.
Mushrooms stand out as one of nature’s best gifts among the natural product sources with their diversity, therapeutic values and increasing popularity. In this study, antioxidant (ABTS•+ scavenging, β-carotene-bleaching, cupric-reducing antioxidant capacity (CUPRAC), DPPH• scavenging, and metal chelating assays), and enzyme (butyrylcholinesterase (BChE) and acetylcholinesterase (AChE), α-amylase and α-glucosidase) inhibition activities of the extracts obtained from Coprinus comatus (O.F. Müll.) Pers., Cerrena unicolor (Bull.) Murrill, Inocutis rheades (Pers.) Fiasson & Niemelä and Leptoporus mollis (Pers.) Quél. mushroom species were investigated. The presence of phenolic and organic acid compounds associated with the bioactive properties of the mushroom species was determined by HPLC-DAD. Fumaric acid was found to be prominent compound in C. comatus (43.90 µg/g dw) and C. unicolor (659.9 µg/g dw), vanillin in L. mollis (19.48 µg/g dw), and p-coumaric acid in I. rheades (21.32 µg/g dw). L. mollis methanol extract, as well as higher antioxidant activity than the standards in CUPRAC and β-carotene-bleaching assays, was noted as superior antioxidant active in all assays (except metal chelating). C. comatus possessed the highest inhibition activity on α-amylase (IC50: 0.23 mg/mL for methanol extract), AChE (IC50: 125.50 µg/mL for hexane extract), and BChE (IC50: 61.03 µg/mL for methanol extract). Also, C. comatus methanol (IC50: 0.09 mg/mL) and L. mollis hexane (IC50: 0.11 mg/ mL) extracts were better α-glucosidase inhibition active than the acarbose (IC50: 0.37 mg/mL). Our study ascertained that the studied mushroom species are particularly sources of biochemically active compounds with therapeutic potential. © 2023 by Begell House, Inc. www.begellhouse.com.

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