PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collections

Permanent URI for this collectionhttps://hdl.handle.net/20.500.13091/5

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Citation - WoS: 25
Citation - Scopus: 22
A Phenyl Glycinol Appended Calix[4]arene Film for Chiral Detection of Ascorbic Acid on Gold Surface
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2019) Akpınar, Merve; Temel, Farabi; Tabakcı, Begüm; Özçelik, Egemen; Tabakcı, Mustafa
This paper describes the synthesis of new chiral calix [4]arene derivative having (R)-2-phenylglycinol moiety (compound 6), and its chiral recognition studies for ascorbic acid (AA) enantiomers by using Quartz Crystal Microbalance (QCM). Initial experiments indicated that the outstanding selective chiral recognition (alpha) was observed as 2.61 for L-enantiomer of AA. The sensitivity (S) and the limit of detection (LOD) values for L-AA were calculated as 0.0226 Hz/mu M and 0.63 mu M, respectively. Furthermore, the sorption behavior and mechanism of AA onto compound 6 film were evaluated and the sorption data exhibited a good correlation with the Freundlich isotherm models. The maximum uptake of L-AA by the sensor was found as 5895.76 mg/g. In conclusion, chiral recognition of AA enantiomers as real-time, sensitive, selective and effective was performed by a calixarene derivative coated QCM sensor.
Citation - WoS: 71
Citation - Scopus: 98
Residual Lstm Layered Cnn for Classification of Gastrointestinal Tract Diseases
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2021) Öztürk, Şaban; Özkaya, Umut
nowadays, considering the number of patients per specialist doctor, the size of the need for automatic medical image analysis methods can be understood. These systems, which are very advantageous compared to manual systems both in terms of cost and time, benefit from artificial intelligence (AI). AI mechanisms that mimic the decision-making process of a specialist increase their diagnosis performance day by day, depending on technological developments. In this study, an AI method is proposed to effectively classify Gastrointestinal (GI) Tract Image datasets containing a small number of labeled data. The proposed AI method uses the convolutional neural network (CNN) architecture, which is accepted as the most successful automatic classification method of today, as a backbone. According to our approach, a shallowly trained CNN architecture needs to be supported by a strong classifier to classify unbalanced datasets robustly. For this purpose, the features in each pooling layer in the CNN architecture are transmitted to an LSTM layer. A classification is made by combining all LSTM layers. All experiments are carried out using AlexNet, GoogLeNet, and ResNet to evaluate the contribution of the proposed residual LSTM structure fairly. Besides, three different experiments are carried out with 2000, 4000, and 6000 samples to determine the effect of sample number change on the proposed method. The performance of the proposed method is higher than other state-of-the-art methods.

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