PubMed İndeksli Yayınlar Koleksiyonu / PubMed Indexed Publications Collections

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Adaptation and Validation of the Post-Pandemic Health Promotion Behavior of Young Adults in the Digital Age (ps-Sgd) Scale in the Turkish Population
(MDPI, 2024) Koç, Mustafa Can; Yıldırım, Elif; Özdurak Singin, Rabia Hürrem; Talaghir, Laurentiu-Gabriel; Iconomescu, Teodora Mihaela; Karakaş, Neşe
Background: Young adulthood is a critical developmental period in which individuals establish life-long health behaviors and take responsibility for their own health care. Health promotion strategies tailored to young adults, leveraging digital tools, and addressing challenges exacerbated by events like the COVID-19 pandemic are needed. The aim of this study was to adapt the post-pandemic health promotion behavior of young adults in the digital age (PS-SGD) scale to the Turkish population in order to assess and compare the health behavior of young adults after the pandemic. Methods: A total of 312 participants, aged between 19 and 29 years, were included in the study via non-probabilistic criterion sampling, while the Turkish adaptation process started with translation and back translation methods performed with three language and two health science experts. For statistical analysis, EFA and CFA were conducted to evaluate internal consistency and structural validity. Confirmatory factor analysis was utilized to confirm the structure of the six sub-dimensions. Additionally, measurement invariance was examined regarding participants' gender to determine if the scale accurately captured similar traits across diverse groups. The relationship between the test-retest data was tested by Pearson correlation to measure consistency and its invariance over time. Results: The gender distribution of the sample was found to be 61.3% female and 38.7% male. According to the results of EFA, items 8 and 18 were removed from the Turkish-adapted version. As a result of the reliability analysis conducted with the Turkish version of the scale, the Cronbach alpha coefficient was obtained as 0.851 for the post-pandemic health promotion behavior. Additionally, the scale was rated as reliable with the following Cronbach alpha values: 0.79 for the personal hygiene, 0.78 for dietary habits, 0.72 for using mobile devices, 0.70 for emotional health, 0.68 for health care and physical activity, and 0.51 for social health sub-dimensions. To examine the six sub-dimension factor structures of the scale, fit indices were calculated as chi 2/df (1.722), GFI (0.894), IFI (0.908), TLI (0.892), CFI (0.907), RMSEA (0.048), and SRMR (0.057) and were within acceptable limits. Findings of the multi-group confirmatory factor analysis for measurement invariance were less than or equal to 0.01 for the triangle CFI and triangle RMSEA values across all indices. Consequently, it was observed that the item-factor structure, factor loadings, variances, covariances, and error variances of the scale were equivalent for both male and female young adults, while test-retest results showed a high positive correlation. Conclusions: The Turkish version of the post-pandemic health promotion behavior scale of young adults in the digital age scale, consisting of 25 items and six subscales, was proven to be a valid and reliable tool to measure health promotion behavior in young adults aged 19-29 years.
Citation - WoS: 2
Citation - Scopus: 3
Alternative Green Application Areas for Olive Pomace Catalytic Pyrolysis Biochar Obtained Via Marble Sludge Catalyst
(Springer, 2024) Göktepeli, Gamze; Özgan, Afra; Önen, Vildan; Ahmetli, Gülnare; Kalem, Merve; Yel, Esra
Evaluating industrial wastes in the system with minimum preprocessing and generation economically valuable products from them have critical importance. In this regard, especially cheap, wieldy, and readily available catalysts have been researched to increase variety of useful products in pyrolysis systems, to reduce process time, and to increase quality and diversity of products. Therefore, in this study, marble sludge (named K1) was evaluated as catalyst at different dosages (10%, 20%, 30%, 50%) and pyrolysis temperatures (300, 500, 700 degrees C) in olive pomace (OP) pyrolysis and; the potential green applications of produced new biochars at new usage areas with different purposes based on characteristics were investigated. ANOVA test results showed that temperature and catalysts ratio had significant effect on pyrolysis product yields since significance value for K1 and temperature was lower than 0.05 for pyrolysis products. OP-K1 biochars had alkaline properties and high earth metal quantities. Moreover, increment in K1 ratio and temperature resulted in decrement of the biochar surface acidity. Therefore, it can be indicated that these biochars can have a potential usage for anaerobic digestion processes, lithium-ion batteries, and direct carbon solid oxide fuel cell (DC-SOFC) but further electrochemical property test should be performed. Moreover, produced biochars can be alternative fuels in some processes instead of coal since they have low S content and high heat values. Consequently, it is foreseen that produced biochars will have an important place in the development of potential usage areas with a new and environmentally friendly approach in different areas apart from the conventional uses of catalytic pyrolysis chars.
Citation - WoS: 1
Citation - Scopus: 1
Analysis of Fluid Forces Impacting on the Impeller of a Mixed Flow Blood Pump With Computational Fluid Dynamics
(Sage Publications Ltd, 2024) Diallo, Abdoulaye Billo; Cinar, Hasan; Yapici, Rafet
This study presents four different impeller designs to compare hydrodynamic forces. Numerical simulation studies are performed via computational fluid dynamics to specify and investigate the hydraulic forces impacting the impeller of the mixed-flow blood pump with a volute. The design point of this pump is that the flow rate is 5 L/min, the rotational speed is 8000 rpm, and the manometric head is 100 mmHg. The designed impellers are placed in the same volute and simulation studies are performed with the same mesh size (17.3 million cells) of the pumps. The simulation studies have been conducted in setting 1050 kg/m3 blood density, 35 cP fluid viscosity, and SST-k omega turbulence model. Additionally, this study examines the changes in hydraulic forces and hydraulic efficiency with fluid viscosity. As a result of experimental simulation studies, the highest hydraulic efficiencies of 40.87% and 39.5% are achieved in the case of the shaftless-grooveless and shafted-grooveless impeller, respectively. The maximum axial forces are obtained from the pump with the shaftless-grooveless impeller. Whereas radial forces, maximum values are calculated in the pump with the shaftless-outer groove impeller for all flow rates. Finally, the wall shear stresses, which are important for blood pump designs, are evaluated and the maximum value of 227 Pa is observed in the pump impeller with a shaftless-grooved.
Citation - WoS: 26
Citation - Scopus: 26
Analysis of Land Use/Land Cover Changes and Prediction of Future Changes With Land Change Modeler: Case of Belek, Turkey
(Springer, 2023) Akdeniz, Halil Burak; Serdaroğlu Sağ, Neslihan; İnam, Şaban
In the areas declared to be a tourism center by state planning, a rapid tourism-related development occurs depending on the investments in tourism, which causes a dramatic land use/land cover (LULC) change. Determining, monitoring, and modeling of LULC changes are required in order to ensure the conservation-use balance and sustainability within such vulnerable areas that are under development pressure. This study consists of four steps. In the first step, the Landsat images dated 1985, 2000, 2010, and 2021 were classified using the maximum likelihood method and the LULC of Belek Tourism Center located in Turkey were determined. The second step included the identification of areal and spatial changes between the LULC classes for the four periods. In the third step, the LULC changes in Belek Tourism Center for 2040 were modeled using the land change modeler. Last step evaluated the relationship between the modeled spatial development pattern and the current planning decisions. According to the results obtained during 36 years, the rates of built-up, forest, and water body areas have increased by 11.91%, 13.67%, and 0.82%, respectively, whereas the rates of barren land and agricultural areas have reduced by 22.25% and 4.15%, respectively. The LULC map modeled for 2040 predicts the built-up areas to expand by 8.25% and the agricultural areas to shrink by 5.42% by comparison with 2021. This study will contribute as a key measure for planners, policy-, and decision-makers to make decisions related to sustainable land use in the areas declared to be a tourism center.
Citation - WoS: 52
Citation - Scopus: 62
Analytical Review of Geopolymer Concrete: Retrospective and Current Issues
(MDPI, 2023) Meskhi, Besarion; Beskopylny, Alexey N.; Stel'makh, Sergey A.; Shcherban, Evgenii M.; Mailyan, Levon R.; Shilov, Alexander A.; El’shaeva, Diana; Shilova, Karolina; Karalar, Memduh; Aksoylu, Ceyhun; Özkılıç, Yasin Onuralp
The concept of sustainable development provides for the search for environmentally friendly alternatives to traditional materials and technologies that would reduce the amount of CO2 emissions into the atmosphere, do not pollute the environment, and reduce energy costs and the cost of production processes. These technologies include the production of geopolymer concretes. The purpose of the study was a detailed in-depth analytical review of studies of the processes of structure formation and properties of geopolymer concretes in retrospect and the current state of the issue. Geopolymer concrete is a suitable, environmentally friendly and sustainable alternative to concrete based on ordinary Portland cement (OPC) with higher strength and deformation properties due to its more stable and denser aluminosilicate spatial microstructure. The properties and durability of geopolymer concretes depend on the composition of the mixture and the proportions of its components. A review of the mechanisms of structure formation, the main directions for the selection of compositions and processes of polymerization of geopolymer concretes has been made. The technologies of combined selection of the composition of geopolymer concrete, production of nanomodified geopolymer concrete, 3D printing of building structures from geopolymer concrete, and monitoring the state of structures using self-sensitive geopolymer concrete are considered. Geopolymer concrete with the optimal ratio of activator and binder has the best properties. Geopolymer concretes with partial replacement of OPC with aluminosilicate binder have a denser and more compact microstructure due to the formation of a large amount of calcium silicate hydrate, which provides improved strength, durability, less shrinkage, porosity and water absorption. An assessment of the potential reduction in greenhouse gas emissions from the production of geopolymer concrete compared to the production of OPC has been made. The potential of using geopolymer concretes in construction practice is assessed in detail.
Citation - WoS: 18
Citation - Scopus: 19
Antibacterial Activity of Linezolid Against Gram-Negative Bacteria: Utilization of Epsilon-Poly Capped Silica Xerogel as an Activating Carrier
(MDPI, 2020) Kaya Güzel, Gülcihan; Medaglia, Serena; Candela-Noguera, Vicente; Tormo-Mas, Maria Angeles; Marcos, Maria Dolores; Aznar, Elena; Martinez-Manez, Ramon
In recent times, many approaches have been developed against drug resistant Gram-negative bacteria. However, low-cost high effective materials which could broaden the spectrum of antibiotics are still needed. In this study, enhancement of linezolid spectrum, normally active against Gram-positive bacteria, was aimed for Gram-negative bacteria growth inhibition. For this purpose, a silica xerogel prepared from a low-cost precursor is used as a drug carrier owing to the advantages of its mesoporous structure, suitable pore and particle size and ultralow density. The silica xerogel is loaded with linezolid and capped with epsilon-poly-l-lysine. The developed nano-formulation shows a marked antibacterial activity against to Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. In comparison to free linezolid and epsilon-poly-l-lysine, the material demonstrates a synergistic effect on killing for the three tested bacteria. The results show that silica xerogels can be used as a potential drug carrier and activity enhancer. This strategy could provide the improvement of antibacterial activity spectrum of antibacterial agents like linezolid and could represent a powerful alternative to overcome antibiotic resistance in a near future.
Citation - WoS: 2
Citation - Scopus: 3
Assessment of University Students' Earthquake Coping Strategies Using Artificial Intelligence Methods
(Nature Portfolio, 2025) Sulak, Suleyman Alpaslan; Koklu, Nigmet
Earthquakes are one of the most destructive natural disasters that pose a serious threat to human life and infrastructure worldwide. The aim of this study is to evaluate the coping strategies of adult individuals in Turkey regarding earthquake stress using artificial intelligence-based methods. The data was collected from 858 university students living in Turkey during January, February, and March 2024. A dataset was created using the 'Coping Scale for Earthquake Stress.' Prediction models were established using artificial intelligence algorithms such as Logistic Regression (LR), Bagging, and Random Forest (RF) based on information from 24 variables. The cross-validation method was applied during model training. The Logistic Regression algorithm achieved the highest accuracy rate of 98.60%, while the Bagging algorithm demonstrated the lowest performance with an accuracy rate of 79.95%. The Random Forest algorithm showed moderate performance with an accuracy rate of 85.89%. The findings provide important insights into the coping strategies of the community regarding earthquake stress. This study is expected to contribute significantly to areas such as disaster management, psychology, public health, and community resilience.
The Association of Food Rejection Behaviours in Preschool Children With Compliance to the Mediterranean Diet and Their Quality of Life: A Cross-Sectional Analysis
(Cambridge Univ Press, 2025) Demir, Gulperi; Kudret, Meltem; Demir, Rabia Sena; Bagci, Sumeyya; Yildirim, Elif
Food refusal behaviours in preschool children can significantly impact their nutritional status and overall quality of life. This study investigated the relationship between food refusal behaviours, compliance with the Mediterranean diet and quality of life in preschool children. Conducted as a cross-sectional study, it included 400 children aged 4-6 years and their parents. The Child Food Rejection Scale measured food refusal behaviours, The Children's Mediterranean Diet Quality Scale (KIDMED) assessed compliance with the Mediterranean Diet and the Children Quality of Life-Questionnaire (Kiddy-KINDL) scale evaluated quality of life. The mean age of the children was 480 (sd 071) years. According to age-based BMI-Z scores, 710 % were normal, 155 % underweight, 90 % slightly overweight and 45 % obese. Parents' average age was 3465 (SD 535) years; 968 % were married, 888 % had a nuclear family structure, 580 % were university graduates and 698 % rated their income level as moderate. Girls had higher food refusal scores than boys (P < 005). Children who frequently fell ill also scored higher in food refusal (P < 005). Food refusal decreased with higher family income, larger family size and older parental age (P < 005). Parental nutrition education significantly reduced food refusal scores (P < 005). Higher KIDMED scores were associated with lower food refusal (P < 001), and children with low Kiddy-KINDL scores exhibited higher food refusal behaviours (P < 001). A positive correlation was found between KIDMED and Kiddy-KINDL scores (P < 001). No significant associations were detected between BMI Z scores and food rejection and its subscales. The findings suggest that compliance with the Mediterranean diet reduces food refusal behaviours in preschool children and increases quality of life, while low quality of life is associated with increased food refusal behaviours.
Citation - WoS: 3
Citation - Scopus: 14
Author Correction: a Portrait of the Higgs Boson by the Cms Experiment Ten Years After the Discovery (nature, (2022), 607, 7917, (60-68), 10.1038/S41586-022-04892-x)
(Nature Research, 2023) Tumasyan A.; Adam W.; Andrejkovic J.W.; Bergauer T.; Chatterjee S.; Damanakis K.; Dragicevic M.; Gürpınar Güler, Emine; Güler, Yalçın
Correction to: Nature Published online 4 July 2022 In the version of this article initially published, CMS Collaboration author names, affiliations and acknowledgements were omitted and have now been included in the HTML and PDF versions of the article. © 2023, The Author(s).
Citation - WoS: 1
Citation - Scopus: 1
Bacterial Microbiome Diversity Along Poultry Slaughtering Lines: Insights From Chicken Carcasses and Environmental Sources
(Sciendo, 2024) Telli, Arife Ezgi; Bicer, Yusuf; Telli, Nihat; Sönmez, Gonca; Turkal, Gamze; Güzel, İsmail
Introduction This study aimed to determine the bacterial diversity of chicken carcasses and their surrounding environment at various stages along a poultry slaughter line.Material and Methods Amplicon sequencing of the 16S rRNA gene was employed to assess the shifts in bacterial community diversity at both phylum and genus levels. Samples were collected from September to November 2021, targeting carcass surfaces at various operational stages (post-defeathering, post-evisceration, post-water chilling, and post-cooling), as well as from the internal environments and air of these units. The study took place in a vertically integrated poultry slaughterhouse in Konya, Turkey.Results Microbial diversity increased after the chilling and storage stages as a result of redistribution of the microorganisms after the physical effect of the slaughtering stages. The final product sample taken after storage had the highest bacterial abundance. The abundance at this stage was found to be strongly correlated with that at other slaughtering stages, as well as with the abundance in chilling water and on the personnel's hands. The common genera in chicken carcasses during slaughter stages were Macrococcus, Acinetobacter, Enterococcus, Escherichia-Shigella, Psychrobacter, Streptococcus, Lactococcus and Ligilactobacillus. Microbiome data in environmental samples indicated that the genera in highest relative abundance were Bacillus, Anoxybacillus, Acinetobacter and Psychrobacter. In air samples, the storage room had the highest diversity and in this place Bacillus spp. and Staphylococcus spp. were in the majority.Conclusion This study may provide some useful information to pinpoint the critical contamination sources in the poultry slaughtering process.
Citation - WoS: 1
Citation - Scopus: 1
Bending Performance of Reinforced Concrete Beams With Partial Waste Glass Aggregate Replacement Assessed by Experimental, Theoretical and Digital Image Correlation Analyses
(Nature Portfolio, 2025) Ozkilic, Yasin Onuralp; Basaran, Bogachan; Aksoylu, Ceyhun; Karalar, Memduh; Zeybek, Ozer; Althaqafi, Essam; Umiye, Osman Ahmed
This study examines the usage of waste glass aggregate (WGA) for the consumption of sustainable reinforced concrete regarding the replacement of fine aggregate (FA) and coarse aggregate (CA). For this purpose, a series of tests consisting of a total of 12 beams were carried out to explore the bending performance. The quantity of the longitudinal reinforcement section area and WGA percentage were selected as the prime variables. For this purpose, the aggregate was swapped with WGA with weight percentages of 10% and 20% for the FA and 10% and 20% for coarse aggregate. The test outcomes revealed that the crack and bending properties of the reinforced concrete beams (RCBs) were greatly affected by the section area of tension reinforcement and the percentage of the WGA. The WGA percentage might be effectively used as 20% of the partial replacement of FA. With the addition of FA to the mixture, the load-bearing capacity of RCB increases. The increase in the WGA percentage by more than 10% might cause a considerable reduction in the capacity of the RCBs, especially when the longitudinal reinforcement ratio is high. Furthermore, the digital image correlation method was used to show the cracks/micro-cracks and to define displacement in RCBs.
Citation - WoS: 36
Citation - Scopus: 40
Buckling Analysis of Cnt-Reinforced Polymer Composite Beam Using Experimental and Analytical Methods
(MDPI, 2023) Madenci, Emrah; Özkılıç, Yasin Onuralp; Aksoylu, Ceyhun; Asyraf, Muhammad Rizal Muhammad; Syamsir, Agusril; Supian, Abu Bakar Mohd; Mamaev, Nicolay
The aim of this article was to investigate the effect of carbon nanotubes (CNTs) on the buckling behavior of fiber-reinforced polymer (FRP) composites. The materials used included three layers: carbon-fiber-reinforced polymer (CFRP), epoxy and CNTs. A set of mechanical tests, such as compression and buckling tests, was performed, and also analytical solutions were developed. Damage analysis was also carried out by controlling the damage initiation and crack progression on the composite samples. Experimental results revealed that using 0.3% with CNT additives enhanced the buckling performance of the composite. Finally, the average load-carrying capacity for the clamped-clamped boundary condition was 268% higher in the CNT samples and 282% higher in the NEAT samples compared to the simple-simple condition.
Citation - WoS: 2
Citation - Scopus: 2
Calixarene-Based Functional Fabric for Simultaneously Adsorptive Removal of Anionic and Cationic Dyes
(Amer Chemical Soc, 2025) Ozcelik, Egemen; Tabakci, Begum; Karaman, Mustafa; Tabakci, Mustafa
This study investigated the adsorptive properties of functionalized fabric containing dimethylaminomethyl calix[4]arene (DMAM-Calix) to remove anionic methyl orange (MO) and cationic Rhodamine B (RhB) dyes in aqueous media. Adsorption studies were performed using a filtration system packed with DMAM-Calix-functionalized fabric (DCF). The results revealed that the cationic and anionic structures work compatibly in a binary mixture medium. Hydrogen bonding, pi-pi, cation-pi, n-pi and electrostatic interactions between dye molecules and DMAM-Calix units of DCF were the main factors affecting the adsorption process. Experiments on real wastewater samples of unknown composition confirmed that the approach could successfully remove MO and RhB dyes from real water samples with high efficiency, especially for RhB. Isotherm and kinetic data for MO were mainly represented by the Langmuir model and pseudo-second-order kinetic model, respectively. The adsorption capacities of DCF were found to be about 4.7 mg g-1 for MO and 1.0 mg g-1 for RhB at pH 6.0, which were evaluated as satisfactory considering the first use of a calixarene-derived coated fabric as an adsorbent, the anionic-cationic dye selectivity of DCF, and the low cost and ease of application of the method.
Citation - WoS: 11
Citation - Scopus: 9
Capture and Release Recyclable Dimethylaminomethyl-Calixarene Functional Cloths for Point-Of Removal of Highly Toxic Chromium Water Pollutants
(AMER CHEMICAL SOC, 2020) Bieber, Vera S.; Özçelik, Egemen; Cox, Harrison J.; Ottley, Christopher J.; Ratan, Jatinder K.; Karaman, Mustafa; Badyal, Jas Pal S.
Chromium(VI) contamination of drinking water arises from industrial activity wherever there is a lack of environmental legislation enforcement regarding the removal of such pollutants. Although it is possible to remove such harmful metal ions from drinking water through large-scale facilities, there currently exists no safe and simple way to filter chromium(VI) oxoanions at the point of use (which is potentially safer and necessary in remote locations or humanitarian scenarios). High-surface-area cloth substrates have been functionalized with calixarene molecules for the selective capture of aqueous chromium(VI) oxoanions in the presence of structurally similar anions. This is accomplished by pulsed plasmachemical deposition of a linker layer and subsequent functionalization with dimethylaminomethyl-calixarene (5,11,17,23-tetrakis [(dimethylamino)methyl]-25,26,27,28-tetrahydroxycalix[4]arene. Chromium(VI) oxoanions are captured by simply passing polluted water through the functionalized cloth, while other ions not harmful/beneficial to human health remain in the water. These cloth filters are simple to use, highly selective, and easily recyclable-thus making them attractive for point-of-use application in geographic regions lacking appropriate wastewater treatment plants or flawed environmental monitoring systems. Chromium(VI) pollutants have been successfully removed from real-world contaminated industrial wastewater streams using the dimethylaminomethyl-calixarene functionalized cloths.
Carbon Nanotube-Supported Bimetallic Core-Shell (m@pd/Cnt (m: Zn, Mn, Ag, Co, V, Ni)) Cathode Catalysts for H2o2 Fuel Cells
(AMER CHEMICAL SOC, 2023) Yapıcı, Burak; Gökdoğan Şahin, Özlem
M@Pd/CNT (M: Zn, Mn, Ag, Co, V, Ni) core-shell and Pd/CNT nanoparticles were prepared by sodium borohydride reduction and explored as cathode catalysts for the hydrogen peroxide reduction reaction. Electrochemical and physical characterization techniques are applied to explore the characteristics of the produced electrocatalysts. The cyclic voltammetry (CV) experiments show that Zn@Pd/CNT-modified electrodes have a current density of 273.2 mA cm(-2), which is 3.95 times higher than that of Pd/CNT. According to the chronoamperometric curves, Zn@Pd/CNT has the highest steady-state current density for the H2O2 electro-reduction process among the synthesized electrocatalysts. Moreover, electrochemical impedance spectroscopy (EIS) spectra confirmed the previous electrochemical results due to the lowest charge transfer resistance (35 Omega) with respect to other electrocatalysts.
Citation - WoS: 12
Citation - Scopus: 16
Characterization of Polysaccharide Extracts of Four Edible Mushrooms and Determination of in Vitro Antioxidant, Enzyme Inhibition and Anticancer Activities
(Amer Chemical Soc, 2024) Deveci, Ebru; Tel-Cayan, Gülsen; Cayan, Fatih; Altinok, Bahar Yilmaz; Aktaş, Sinan
Mushroom polysaccharides are important bioactive compounds derived from mushrooms with various beneficial properties. In this study, the chemical characterization and bioactivities of polysaccharide extracts from four different edible mushrooms, Clavariadelphus truncatus Donk, Craterellus tubaeformis (Fr.) Quel., Hygrophorus pudorinus (Fr.) Fr., and Macrolepiota procera (Scop.) Singer were studied. Glucose (13.24-56.02%), galactose (14.18-64.05%), mannose (2.18-18.13%), fucose (1.21-5.78%), and arabinose (0.04-5.43%) were identified in all polysaccharide extracts by GC-MS (gas chromatography-mass spectrometry). FT-IR (Fourier transform infrared spectroscopy) confirmed the presence of characteristic carbohydrate patterns. H-1 NMR suggested that all polysaccharide extracts had alpha- and beta-d-mannopyranose, d-glucopyranose, d-galactopyranose, alpha-l-arabinofuranose, and alpha-l-fucopyranose residues. Approximate molecular weights of polysaccharide extracts were determined by HPLC (high-performance liquid chromatography). The best antioxidant activity was found in M. procera polysaccharide extract in DPPH center dot (1,1-diphenyl-2-picrylhydrazyl) scavenging (39.03% at 800 mu g/mL), CUPRAC (cupric reducing antioxidant capacity) (A(0.50): 387.50 mu g/mL), and PRAP (phosphomolybdenum reducing antioxidant power) (A(0.50): 384.08 mu g/mL) assays. C. truncatus polysaccharide extract showed the highest antioxidant activity in ABTS(center dot+) scavenging (IC50: 734.09 mu g/mL), beta-carotene-linoleic acid (IC50: 472.16 mu g/mL), and iron chelating (IC50: 180.35 mu g/mL) assays. Significant anticancer activity was found in C. truncatus polysaccharide extract on HT-29 (IC50: 46.49 mu g/mL) and HepG2 (IC50: 48.50 mu g/mL) cell lines and H. pudorinus polysaccharide extract on the HeLa cell line (IC50: 51.64 mu g/mL). Also, H. pudorinus polysaccharide extract possessed prominent AChE (acetylcholinesterase) inhibition activity (49.14% at 200 mu g/mL).
Citation - WoS: 67
Citation - Scopus: 108
Classification of Coronavirus (covid-19) Fromx-Rayandctimages Using Shrunken Features
(WILEY, 2021) Öztürk, Şaban; Özkaya, Umut; Barstuğan, Mücahid
Necessary screenings must be performed to control the spread of the COVID-19 in daily life and to make a preliminary diagnosis of suspicious cases. The long duration of pathological laboratory tests and the suspicious test results led the researchers to focus on different fields. Fast and accurate diagnoses are essential for effective interventions for COVID-19. The information obtained by using X-ray and Computed Tomography (CT) images is vital in making clinical diagnoses. Therefore it is aimed to develop a machine learning method for the detection of viral epidemics by analyzing X-ray and CT images. In this study, images belonging to six situations, including coronavirus images, are classified using a two-stage data enhancement approach. Since the number of images in the dataset is deficient and unbalanced, a shallow image augmentation approach was used in the first phase. It is more convenient to analyze these images with hand-crafted feature extraction methods because the dataset newly created is still insufficient to train a deep architecture. Therefore, the Synthetic minority over-sampling technique algorithm is the second data enhancement step of this study. Finally, the feature vector is reduced in size by using a stacked auto-encoder and principal component analysis methods to remove interconnected features in the feature vector. According to the obtained results, it is seen that the proposed method has leveraging performance, especially to make the diagnosis of COVID-19 in a short time and effectively. Also, it is thought to be a source of inspiration for future studies for deficient and unbalanced datasets.
Citation - WoS: 237
Citation - Scopus: 311
Cnn-Based Transfer Learning-Bilstm Network: a Novel Approach for Covid-19 Infection Detection
(ELSEVIER, 2021) Aslan, Muhammet Fatih; Ünlerşen, Muhammed Fahri; Sabancı, Kadir; Durdu, Akif
Coronavirus disease 2019 (COVID-2019), which emerged in Wuhan, China in 2019 and has spread rapidly all over the world since the beginning of 2020, has infected millions of people and caused many deaths. For this pandemic, which is still in effect, mobilization has started all over the world, and various restrictions and precautions have been taken to prevent the spread of this disease. In addition, infected people must be identified in order to control the infection. However, due to the inadequate number of Reverse Transcription Polymerase Chain Reaction (RT-PCR) tests, Chest computed tomography (CT) becomes a popular tool to assist the diagnosis of COVID-19. In this study, two deep learning architectures have been proposed that automatically detect positive COVID-19 cases using Chest CT X-ray images. Lung segmentation (preprocessing) in CT images, which are given as input to these proposed architectures, is performed automatically with Artificial Neural Networks (ANN). Since both architectures contain AlexNet architecture, the recommended method is a transfer learning application. However, the second proposed architecture is a hybrid structure as it contains a Bidirectional Long Short-Term Memories (BiLSTM) layer, which also takes into account the temporal properties. While the COVID-19 classification accuracy of the first architecture is 98.14%, this value is 98.70% in the second hybrid architecture. The results prove that the proposed architecture shows outstanding success in infection detection and, therefore this study contributes to previous studies in terms of both deep architectural design and high classification success. (C) 2020 Elsevier B.V. All rights reserved.
Co-Occurrence and Molecular Characterization of ESBL-Producing and Colistin-Resistant Escherichia Coli Isolates From Retail Raw Meat
(MDPI, 2025) Telli, Arife Ezgi; Telli, Nihat; Bicer, Yusuf; Turkal, Gamze; Yilmaz, Tahir; Ucar, Gurkan
Background: The emergence of extended-spectrum beta-lactamase (ESBL) producing and colistin-resistant Escherichia coli in retail meat poses a significant public health risk. Method: A total of 180 retail meat samples (chicken parts, internals, processed products; lamb; beef; fish) were purchased from markets and butcher shops across Turkiye. Presumptive ESBL-producing isolates were screened on chromogenic agar and phenotypically confirmed. Species identity was verified by uspA PCR, and resistance genes (blaCTX-M, blaTEM, blaOXA, blaSHV, mcr-1, mcr-2, mcr-3) were analyzed. Colistin MICs were determined by broth microdilution, while antimicrobial susceptibility of ESBL-positive isolates was assessed by disk diffusion. Results: Overall, ESBL-producing E. coli were detected in 21.7% (n = 39) of the 180 meat samples analyzed, with the highest prevalence observed in chicken parts (26/40, 65.0%) and giblets (6/10, 60%). All ESBL-E. coli isolates harbored blaCTX-M, with blaCTX-M-1 identified as the sole variant. The blaTEM gene was detected in 61.5% (24/39) of ESBL-positive E. coli isolates. Colistin resistance was identified in six isolates (15.4%), all of which carried the mcr-1 gene. Additionally, one lamb minced meat isolate harbored the mcr-2 gene. Co-occurrence analysis revealed that the most frequent resistance gene combination among ESBL-producing isolates was blaCTX-M1 + blaTEM, detected predominantly in chicken meat samples, while mcr-1 was observed only in isolates harboring single or limited resistance genes, suggesting a distinct acquisition pattern. Conclusions: A high prevalence of blaCTX-M-1 and the co-occurrence of mcr genes were detected in E. coli isolates from retail meat, particularly poultry. The detection of mcr-1/mcr-2 co-carriage in lamb meat, though rare, highlights the need for broader surveillance. These findings underscore the need for integrated monitoring and prudent antimicrobial use in food animals. The use of antibiotics as growth promoters is prohibited in T & uuml;rkiye, and therapeutic applications require a veterinary prescription; however, stronger enforcement remains essential to limit the dissemination of multidrug-resistant bacteria in the food chain.
Citation - WoS: 34
Citation - Scopus: 49
Combined Searches for the Production of Supersymmetric Top Quark Partners in Proton-Proton Collisions at Root S=13 Tev
(SPRINGER, 2021) Tumasyan, A.; Adam, W.; Andrejkovic, J. W.; Bergauer, T.; Chatterjee, S.; Dragicevic, M.; Vetens, W.; Gürpınar Güler, Emine; Güler, Yalçın; The CMS Collaboration
A combination of searches for top squark pair production using proton-proton collision data at a center-of-mass energy of 13 TeV at the CERN LHC, corresponding to an integrated luminosity of 137 fb(-1) collected by the CMS experiment, is presented. Signatures with at least 2 jets and large missing transverse momentum are categorized into events with 0, 1, or 2 leptons. New results for regions of parameter space where the kinematical properties of top squark pair production and top quark pair production are very similar are presented. Depending on themodel, the combined result excludes a top squarkmass up to 1325 GeV for amassless neutralino, and a neutralinomass up to 700 GeV for a top squarkmass of 1150 GeV. Top squarks with masses from 145 to 295 GeV, for neutralino masses from 0 to 100 GeV, with a mass difference between the top squark and the neutralino in a window of 30 GeV around the mass of the top quark, are excluded for the first time with CMS data. The results of theses searches are also interpreted in an alternative signal model of dark matter production via a spin-0 mediator in association with a top quark pair. Upper limits are set on the cross section for mediator particle masses of up to 420 GeV.

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