Please use this identifier to cite or link to this item:
https://hdl.handle.net/20.500.13091/1587
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yılmaz, N. | - |
dc.contributor.author | Edebali, S. | - |
dc.contributor.author | İçduygu, M.G. | - |
dc.date.accessioned | 2021-12-13T10:41:35Z | - |
dc.date.available | 2021-12-13T10:41:35Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 1753-2507 | - |
dc.identifier.uri | https://doi.org/10.1504/IJNP.2020.112398 | - |
dc.identifier.uri | https://hdl.handle.net/20.500.13091/1587 | - |
dc.description.abstract | In this study, synthesis and characterisation of mesoporous, super magnetic silica with controlled release methotrexate ability were aimed for treatment of rheumatoid arthritis. Within this scope, magnetite nanoparticles were synthesised by coprecipitation method and surfaces of these nanoparticles were coated with mesoporous silica and phospholipid layers. FT-IR, XRD, VSM, BET, TEM, EDX and FESEM analyses were performed for characterisation. The results of FT-IR analysis show the existence of silica and lipid layers around magnetite. Fe3O4@SiO2nanoparticles have a surface area of 576.69 m2/g, a pore size of 8.21 nm and a mesoporous structure. XRD analyses indicate that the synthesised Fe3O4 and Fe3O4@SiO2nanoparticles have cubic spinel structures. FESEM images show that nanoparticles have spherical shape and VSM analysis indicates that nanoparticles have superparamagnetic characteristic. © 2020 Inderscience Enterprises Ltd.. All rights reserved. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Inderscience Publishers | en_US |
dc.relation.ispartof | International Journal of Nanoparticles | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Cancer | en_US |
dc.subject | Controlled release | en_US |
dc.subject | Core-shell structured | en_US |
dc.subject | Drug delivery | en_US |
dc.subject | Lipid coated | en_US |
dc.subject | Magnetic silica nanoparticles | en_US |
dc.subject | Magnetite nanoparticles | en_US |
dc.subject | MTX | en_US |
dc.subject | Phospholipid layer | en_US |
dc.subject | Rheumatoid arthritis | en_US |
dc.title | Preparation and characterisation of Fe3O4@SiO2@MTX@Lipid nanoparticles as a controlled drug-delivery system | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1504/IJNP.2020.112398 | - |
dc.identifier.scopus | 2-s2.0-85099542047 | en_US |
dc.department | Fakülteler, Mühendislik ve Doğa Bilimleri Fakültesi, Kimya Mühendisliği Bölümü | en_US |
dc.identifier.volume | 12 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 275 | en_US |
dc.identifier.endpage | 288 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 57193720376 | - |
dc.authorscopusid | 35760236600 | - |
dc.authorscopusid | 6507125347 | - |
dc.identifier.scopusquality | Q4 | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.openairetype | Article | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | 02.01. Department of Chemical Engineering | - |
Appears in Collections: | Mühendislik ve Doğa Bilimleri Fakültesi Koleksiyonu Scopus İndeksli Yayınlar Koleksiyonu / Scopus Indexed Publications Collections |
CORE Recommender
Items in GCRIS Repository are protected by copyright, with all rights reserved, unless otherwise indicated.